Table 2.

Red-cell indices of WT and homozygous ΔHS-62.5, Δ3′HS1 mice


Genotype*

RBC, × 1012/L

Hgb, g/L

HCT, %

MCV, fL

MCH, μg

MCHC, %

Reticulocyte, %
WT   10.11 ± 0.26   171.5 ± 3.1   50.35 ± 1.32   50.00 ± 0.00   17.0 ± 0.26   34.13 ± 0.63   2.54 ± 0.6  
ΔHS-62.5, Δ3′HS1
 
9.75 ± 0.72
 
173.3 ± 6.9
 
49.30 ± 3.59
 
50.75 ± 0.96
 
17.83 ± 0.85
 
35.25 ± 1.38
 
2.89 ± 0.44
 

Genotype*

RBC, × 1012/L

Hgb, g/L

HCT, %

MCV, fL

MCH, μg

MCHC, %

Reticulocyte, %
WT   10.11 ± 0.26   171.5 ± 3.1   50.35 ± 1.32   50.00 ± 0.00   17.0 ± 0.26   34.13 ± 0.63   2.54 ± 0.6  
ΔHS-62.5, Δ3′HS1
 
9.75 ± 0.72
 
173.3 ± 6.9
 
49.30 ± 3.59
 
50.75 ± 0.96
 
17.83 ± 0.85
 
35.25 ± 1.38
 
2.89 ± 0.44
 

Hgb indicates hemoglobin level; HCT, hematocrit; MCV, mean cell volume; MCH, mean cell hemoglobin; and MCHC, mean cell hemoglobin concentration. Values are expressed ± SD. Automated complete blood counts were obtained from WT and homozygous ΔHS-62.5, Δ3′HS1 mice; red-cell indices are displayed. Reticulocyte counts were determined by flow cytometry after staining with RetiCount (Becton Dickinson, San Jose, CA).

*

For each genotype, N = 4.

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