Comparison of long-term male survivors with and without detectable spermatozoa in the seminal fluid
. | Semen analysis results . | . | . | |
|---|---|---|---|---|
| Characteristics . | Without sperm . | With sperm . | P . | |
| No. patients (%) | 28 (72) | 11 (28) | ||
| Median age at HSCT, y (range) | 28 (16-56) | 19 (5-42) | .004 | |
| Median length of follow-up in y (range) | 7 (2-20) | 12 (3-19) | .01 | |
| Diseases, no. (%) | .008 | |||
| Aplastic anemia | 0 (0) | 3 (27) | ||
| Acute leukemia | 13 (47) | 8 (73) | ||
| Chronic myeloid leukemia | 11 (39) | 0 (0) | ||
| Other malignancies | 4 (14) | 0 (0) | ||
| Donor type, no. (%) | .1 | |||
| HLA-matched unrelated | 7 (25) | 0 (0) | ||
| HLA-matched sibling | 21 (75) | 11 (100) | ||
| Donor sex, no. (%) | .7 | |||
| Male | 16 (57) | 7 (64) | ||
| Female | 12 (43) | 4 (36) | ||
| TBI 10 Gy or more, no. (%) | .08 | |||
| No | 3 (11) | 4 (37) | ||
| Yes | 25 (89) | 7 (63) | ||
| Acute GvHD, no. (%) | .7 | |||
| None or grade I | 13 (47) | 4 (37) | ||
| Grade II-IV | 15 (53) | 7 (63) | ||
| Chronic GvHD | .03 | |||
| None, no. (%) | 12 (43) | 9 (82) | ||
| Any grade, no. (%) | 16 (57) | 2 (18) | ||
| Time free of chronic GvHD, d, median (range) | 1815 (0-6314) | 4237 (0-6912) | .05 | |
. | Semen analysis results . | . | . | |
|---|---|---|---|---|
| Characteristics . | Without sperm . | With sperm . | P . | |
| No. patients (%) | 28 (72) | 11 (28) | ||
| Median age at HSCT, y (range) | 28 (16-56) | 19 (5-42) | .004 | |
| Median length of follow-up in y (range) | 7 (2-20) | 12 (3-19) | .01 | |
| Diseases, no. (%) | .008 | |||
| Aplastic anemia | 0 (0) | 3 (27) | ||
| Acute leukemia | 13 (47) | 8 (73) | ||
| Chronic myeloid leukemia | 11 (39) | 0 (0) | ||
| Other malignancies | 4 (14) | 0 (0) | ||
| Donor type, no. (%) | .1 | |||
| HLA-matched unrelated | 7 (25) | 0 (0) | ||
| HLA-matched sibling | 21 (75) | 11 (100) | ||
| Donor sex, no. (%) | .7 | |||
| Male | 16 (57) | 7 (64) | ||
| Female | 12 (43) | 4 (36) | ||
| TBI 10 Gy or more, no. (%) | .08 | |||
| No | 3 (11) | 4 (37) | ||
| Yes | 25 (89) | 7 (63) | ||
| Acute GvHD, no. (%) | .7 | |||
| None or grade I | 13 (47) | 4 (37) | ||
| Grade II-IV | 15 (53) | 7 (63) | ||
| Chronic GvHD | .03 | |||
| None, no. (%) | 12 (43) | 9 (82) | ||
| Any grade, no. (%) | 16 (57) | 2 (18) | ||
| Time free of chronic GvHD, d, median (range) | 1815 (0-6314) | 4237 (0-6912) | .05 | |
N = 39.