Correlation between CASP8AP2 gene expression and presenting clinicobiologic features
. | . | CASP8AP2 expression, no. . | . | . | . | ||
---|---|---|---|---|---|---|---|
Presenting feature . | Patients studied, no. . | Lower . | Middle . | Higher . | P* . | ||
Age | |||||||
Younger than 1 y | 9 | 7 | 1 | 1 | .016 | ||
1 to 9 y | 203 | 58 | 71 | 74 | |||
10 y or older | 76 | 31 | 24 | 21 | |||
Race | |||||||
White | 214 | 74 | 67 | 73 | .401 | ||
Black | 55 | 19 | 21 | 15 | |||
Other | 19 | 3 | 8 | 8 | |||
Sex | |||||||
Male | 169 | 58 | 56 | 55 | .905 | ||
Female | 119 | 38 | 40 | 41 | |||
WBC, × 109/L | |||||||
Less than 10 | 90 | 27 | 30 | 33 | .328 | ||
10 to 50 | 85 | 27 | 26 | 32 | |||
50 to 100 | 52 | 16 | 17 | 19 | |||
More than 100 | 61 | 26 | 23 | 12 | |||
BCR-ABL | |||||||
Present | 16 | 6 | 5 | 5 | .936 | ||
Absent | 272 | 90 | 91 | 91 | |||
TEL-AML1 | |||||||
Present | 57 | 15 | 19 | 23 | .352 | ||
Absent | 231 | 81 | 77 | 73 | |||
MLL-AF4 | |||||||
Present | 18 | 10 | 5 | 3 | .099 | ||
Absent | 270 | 86 | 91 | 93 | |||
Ploidy | |||||||
Hyperdiploid† | 52 | 8 | 15 | 29 | < .001 | ||
Others | 236 | 88 | 81 | 67 | |||
DNA index | |||||||
1.16 or higher | 47 | 8 | 11 | 28 | < .001 | ||
Less than 1.16 | 241 | 88 | 85 | 68 |
. | . | CASP8AP2 expression, no. . | . | . | . | ||
---|---|---|---|---|---|---|---|
Presenting feature . | Patients studied, no. . | Lower . | Middle . | Higher . | P* . | ||
Age | |||||||
Younger than 1 y | 9 | 7 | 1 | 1 | .016 | ||
1 to 9 y | 203 | 58 | 71 | 74 | |||
10 y or older | 76 | 31 | 24 | 21 | |||
Race | |||||||
White | 214 | 74 | 67 | 73 | .401 | ||
Black | 55 | 19 | 21 | 15 | |||
Other | 19 | 3 | 8 | 8 | |||
Sex | |||||||
Male | 169 | 58 | 56 | 55 | .905 | ||
Female | 119 | 38 | 40 | 41 | |||
WBC, × 109/L | |||||||
Less than 10 | 90 | 27 | 30 | 33 | .328 | ||
10 to 50 | 85 | 27 | 26 | 32 | |||
50 to 100 | 52 | 16 | 17 | 19 | |||
More than 100 | 61 | 26 | 23 | 12 | |||
BCR-ABL | |||||||
Present | 16 | 6 | 5 | 5 | .936 | ||
Absent | 272 | 90 | 91 | 91 | |||
TEL-AML1 | |||||||
Present | 57 | 15 | 19 | 23 | .352 | ||
Absent | 231 | 81 | 77 | 73 | |||
MLL-AF4 | |||||||
Present | 18 | 10 | 5 | 3 | .099 | ||
Absent | 270 | 86 | 91 | 93 | |||
Ploidy | |||||||
Hyperdiploid† | 52 | 8 | 15 | 29 | < .001 | ||
Others | 236 | 88 | 81 | 67 | |||
DNA index | |||||||
1.16 or higher | 47 | 8 | 11 | 28 | < .001 | ||
Less than 1.16 | 241 | 88 | 85 | 68 |