Coagulation parameters in warfarinized and control mice
. | Prothrombin time, s . | FIX:C, human U/mL . |
|---|---|---|
| Mouse no. | ||
| 1 | > 300 | < 0.03 |
| 2 | > 300 | < 0.03 |
| 3 | > 300 | < 0.03 |
| 4 | > 300 | < 0.03 |
| 5 | > 300 | < 0.03 |
| 6 | 11.2 | ND |
| 7 | 10.4 | 0.55 |
| 8 | 11.0 | 0.52 |
| 9 | 10.6 | 0.47 |
| 10 | 9.8 | 0.57 |
| Normal mouse pool | 10.6 | 1.05 |
. | Prothrombin time, s . | FIX:C, human U/mL . |
|---|---|---|
| Mouse no. | ||
| 1 | > 300 | < 0.03 |
| 2 | > 300 | < 0.03 |
| 3 | > 300 | < 0.03 |
| 4 | > 300 | < 0.03 |
| 5 | > 300 | < 0.03 |
| 6 | 11.2 | ND |
| 7 | 10.4 | 0.55 |
| 8 | 11.0 | 0.52 |
| 9 | 10.6 | 0.47 |
| 10 | 9.8 | 0.57 |
| Normal mouse pool | 10.6 | 1.05 |
Animals 1 to 5 were warfarinized, and 6 to 10 received no warfarin. Citrated plasma samples taken 1 hour after virus administration were assessed by prothrombin time and 1-stage FIX:C assay (results given in human U/mL FIX)
ND indicates not determined