Baseline characteristics of the patients
. | Arm A; n = 200 . | Arm B; n = 196 . | Arm C; n = 201 . |
---|---|---|---|
Sex, M/F, no. of patients | 110/90 | 109/87 | 112/89 |
Age, y | 59 ± 8* | 59 ± 8 | 58 ± 8 |
DS stage I/II/III, no. of patients | 19/50/131 | 16/34/146 | 16/42/143 |
M component, no. of patients | |||
IgG | 124 | 129 | 119 |
IgA | 47 | 32 | 52 |
Bence Jones | 24 | 30 | 28 |
IgD | 5 | 5 | 2 |
Hemoglobin, g/dL | 11.3 ± 2 | 11.2 ± 2 | 11.1 ± 2 |
Serum calcium, μM | 2.4 ± 0.2 | 2.4 ± 0.3 | 2.4 ± 0.4 |
Serum albumin, g/L | 40 ± 7 | 40 ± 8 | 39 ± 7 |
Lactate dehydrogenase, IU | 321 ± 146 | 336 ± 146 | 311 ± 143 |
Serum creatinine, μM | 101 ± 64 | 101 ± 67 | 101 ± 57 |
Bone marrow plasmocytosis, % of cells | 30 ± 24 | 34 ± 24 | 31 ± 25 |
Serum β-2 microglobulin, mg/L | 3.4 ± 3 | 3.3 ± 2.5 | 3.7 ± 5 |
C reactive protein, mg/L | 10 ± 16 | 10 ± 18 | 11 ± 23 |
Chromosome 13, no. of patients | |||
No deletion | 134 | 136 | 142 |
Deletion | 60 | 56 | 55 |
Unknown | 6 | 4 | 4 |
. | Arm A; n = 200 . | Arm B; n = 196 . | Arm C; n = 201 . |
---|---|---|---|
Sex, M/F, no. of patients | 110/90 | 109/87 | 112/89 |
Age, y | 59 ± 8* | 59 ± 8 | 58 ± 8 |
DS stage I/II/III, no. of patients | 19/50/131 | 16/34/146 | 16/42/143 |
M component, no. of patients | |||
IgG | 124 | 129 | 119 |
IgA | 47 | 32 | 52 |
Bence Jones | 24 | 30 | 28 |
IgD | 5 | 5 | 2 |
Hemoglobin, g/dL | 11.3 ± 2 | 11.2 ± 2 | 11.1 ± 2 |
Serum calcium, μM | 2.4 ± 0.2 | 2.4 ± 0.3 | 2.4 ± 0.4 |
Serum albumin, g/L | 40 ± 7 | 40 ± 8 | 39 ± 7 |
Lactate dehydrogenase, IU | 321 ± 146 | 336 ± 146 | 311 ± 143 |
Serum creatinine, μM | 101 ± 64 | 101 ± 67 | 101 ± 57 |
Bone marrow plasmocytosis, % of cells | 30 ± 24 | 34 ± 24 | 31 ± 25 |
Serum β-2 microglobulin, mg/L | 3.4 ± 3 | 3.3 ± 2.5 | 3.7 ± 5 |
C reactive protein, mg/L | 10 ± 16 | 10 ± 18 | 11 ± 23 |
Chromosome 13, no. of patients | |||
No deletion | 134 | 136 | 142 |
Deletion | 60 | 56 | 55 |
Unknown | 6 | 4 | 4 |
All such values are means ± SD.