Hematocrit, total Hb, and plasma Hb (before and 30 minutes after introduction of CFH solutions)
. | Hematocrit . | . | Total Hb, %, g/dL . | . | Plasma Hb, g/dL . | Estimated blood volume (normalized to baseline)* . | ||
|---|---|---|---|---|---|---|---|---|
. | Baseline . | 30 min . | Baseline . | 30 min . | 30 min . | 30 min . | ||
| Saline | 46.2 ± 1.9 | 47.1 ± 1.7 | 15.5 ± 0.7 | 15.5 ± 0.9 | – | – | ||
| ααHb | 47.8 ± 2.6 | 47.3 ± 2.4 | 15.2 ± 0.9 | 15.1 ± 1.0 | 0.50 ± 0.00† | 1.04 | ||
| PBH4 | 45.4 ± 2.1 | 44.0 ± 1.5 | 13.8 ± 0.6 | 13.9 ± 0.6 | 0.46 ± 0.05† | 1.03 | ||
| MP4 | 45.2 ± 1.6 | 44.7 ± 3.5 | 13.8 ± 0.5 | 13.0 ± 1.1 | 0.38 ± 0.10† | 1.09 | ||
| PBH | 46.5 ± 2.2 | 45.7 ± 2.1 | 14.8 ± 1.1 | 15.1 ± 1.1 | 1.95 ± 0.43‡ | 1.13 | ||
. | Hematocrit . | . | Total Hb, %, g/dL . | . | Plasma Hb, g/dL . | Estimated blood volume (normalized to baseline)* . | ||
|---|---|---|---|---|---|---|---|---|
. | Baseline . | 30 min . | Baseline . | 30 min . | 30 min . | 30 min . | ||
| Saline | 46.2 ± 1.9 | 47.1 ± 1.7 | 15.5 ± 0.7 | 15.5 ± 0.9 | – | – | ||
| ααHb | 47.8 ± 2.6 | 47.3 ± 2.4 | 15.2 ± 0.9 | 15.1 ± 1.0 | 0.50 ± 0.00† | 1.04 | ||
| PBH4 | 45.4 ± 2.1 | 44.0 ± 1.5 | 13.8 ± 0.6 | 13.9 ± 0.6 | 0.46 ± 0.05† | 1.03 | ||
| MP4 | 45.2 ± 1.6 | 44.7 ± 3.5 | 13.8 ± 0.5 | 13.0 ± 1.1 | 0.38 ± 0.10† | 1.09 | ||
| PBH | 46.5 ± 2.2 | 45.7 ± 2.1 | 14.8 ± 1.1 | 15.1 ± 1.1 | 1.95 ± 0.43‡ | 1.13 | ||
Estimated blood volume expansion from baseline = total Hb(baseline)/[total Hb(30 min)–plasma Hb(30 min)]
P = .022 among the 4 g/dL CFH; P = .05 relative to other groups, pairwise comparison between (1) MP4 versus PBH4 (P = .057), (2) PBH4 versus ααHb (P = .338), and (3) MP4 vs ααHb (P = .012)
P < .05 relative to 4 g/dL CFHs