Table 3.

Summary of mutations in the various PT523-resistant sublines

Nucleotide alteration*
Amino acid alteration
Transporter location
Thymidine 523 to cytosine (T523C)   Leu143Pro   TMD4  
C535T   Ala147Val   L4  
C537G   Arg148Gly   L4  
C543T
 		 Gln150Stop
 		 L4
 
Nucleotide alteration*
Amino acid alteration
Transporter location
Thymidine 523 to cytosine (T523C)   Leu143Pro   TMD4  
C535T   Ala147Val   L4  
C537G   Arg148Gly   L4  
C543T
 		 Gln150Stop
 		 L4
 
*

Nucleotide positions are numbered according to accession number U19720

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