Table 4.

FCM data from 40 controls and 15 LGw/oRS patients in the second cohort (prospective analysis)



Controls

LGw/oRS patients
FCM data
Mean
SD
No. outside RR*
Mean
SD
No. outside RR*
Hematogones in all CD34+ cells   13.94   8.22   3   5.68   7.66   10  
CD34+ myeloblasts in all nucleated cells   1.11   0.54   1   2.07   1.63   4  
Antigen expression on CD34+ myeloblasts       
    Lymphoid antigens        
        CD2   1.04   0.12   0   1.02   0.14   0  
        CD4   1.62   0.40   0   2.19   1.70   3  
        CD10   0.96   0.12   0   0.89   0.13   0  
        CD56   0.91   0.06   0   1.05   0.18   4  
    Myeloid antigens        
        CD11b   1.61   0.33   0   1.46   0.55   1  
        CD13   10.10   4.14   2   20.98   15.93   6  
        CD15   2.33   0.62   0   3.06   1.98   3  
        CD33   5.34   1.46   0   9.38   5.56   2  
    Immaturity-related antigens        
        CD117   10.19   3.50   1   20.28   13.94   7  
        CD123   1.43   0.36   0   1.79   0.68   0  
        CD133
 
2.17
 
0.94
 
2
 
2.62
 
1.52
 
3
 


Controls

LGw/oRS patients
FCM data
Mean
SD
No. outside RR*
Mean
SD
No. outside RR*
Hematogones in all CD34+ cells   13.94   8.22   3   5.68   7.66   10  
CD34+ myeloblasts in all nucleated cells   1.11   0.54   1   2.07   1.63   4  
Antigen expression on CD34+ myeloblasts       
    Lymphoid antigens        
        CD2   1.04   0.12   0   1.02   0.14   0  
        CD4   1.62   0.40   0   2.19   1.70   3  
        CD10   0.96   0.12   0   0.89   0.13   0  
        CD56   0.91   0.06   0   1.05   0.18   4  
    Myeloid antigens        
        CD11b   1.61   0.33   0   1.46   0.55   1  
        CD13   10.10   4.14   2   20.98   15.93   6  
        CD15   2.33   0.62   0   3.06   1.98   3  
        CD33   5.34   1.46   0   9.38   5.56   2  
    Immaturity-related antigens        
        CD117   10.19   3.50   1   20.28   13.94   7  
        CD123   1.43   0.36   0   1.79   0.68   0  
        CD133
 
2.17
 
0.94
 
2
 
2.62
 
1.52
 
3
 

Mean, SD, and RR are percentages (hematogones in all CD34+ cells and CD34+ myeloblasts in all nucleated cells) or RMFI (other parameters). For the controls, n = 40; for LGw/oRS patients, n = 15.

*

Number of patients or controls outside RR, out of the patients or controls analyzed. RRs are the same as those shown in Table 2.

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