Table 1.

Clinical characteristics of 361 patients older than 60 with AML


Characteristic

Value
No. of female patients (%)   166 (46)  
Median age, y (range)   67 (61-84)  
Disease status, no. of patients (%)  
    De novo AML   231 (64)  
        M0   13 (6)  
        M1   40 (17)  
        M2   66 (29)  
        M3   13 (6)  
        M4   53 (23)  
        M5   22 (10)  
        M6   3 (1)  
        M7   1 (0)  
        Missing   20 (9)  
    Secondary AML   119 (33)  
        Preceding MDS   78 (22)  
        Preceding malignancy   41 (11)  
        Missing   11 (3)  
Median hemoglobin level, g/L  91 (38-172)  
    Missing, no. of patients (%)   17 (5)  
Median platelet count, × 109/L (range)  61.5 (4-848)  
    Missing, no. of patients (%)   17 (5)  
Median WBC count, × 109/L (range)  8.4 (0.2-303)  
    Missing, no. of patients (%)   16 (4)  
Median PB blasts, % (range)  31 (0-100)  
    Missing, no. of patients (%)   66 (18)  
Median BM blasts, % (range)  70 (0-100)  
    Missing, no. of patients (%)   55 (15)  
Median LDH level, U/L (range)  358 (57-6623)  
    Missing, no. of patients (%)   32 (9)  
Lymphadenopathy, no. of patients (%)  46 (13)  
    Missing   42 (12)  
Gum hypertrophy, no. of patients (%)  14 (4)  
    Missing   28 (8)  
Extramedullary involvement, no. of patients (%)  16 (4)  
    Missing
 
37 (10)
 

Characteristic

Value
No. of female patients (%)   166 (46)  
Median age, y (range)   67 (61-84)  
Disease status, no. of patients (%)  
    De novo AML   231 (64)  
        M0   13 (6)  
        M1   40 (17)  
        M2   66 (29)  
        M3   13 (6)  
        M4   53 (23)  
        M5   22 (10)  
        M6   3 (1)  
        M7   1 (0)  
        Missing   20 (9)  
    Secondary AML   119 (33)  
        Preceding MDS   78 (22)  
        Preceding malignancy   41 (11)  
        Missing   11 (3)  
Median hemoglobin level, g/L  91 (38-172)  
    Missing, no. of patients (%)   17 (5)  
Median platelet count, × 109/L (range)  61.5 (4-848)  
    Missing, no. of patients (%)   17 (5)  
Median WBC count, × 109/L (range)  8.4 (0.2-303)  
    Missing, no. of patients (%)   16 (4)  
Median PB blasts, % (range)  31 (0-100)  
    Missing, no. of patients (%)   66 (18)  
Median BM blasts, % (range)  70 (0-100)  
    Missing, no. of patients (%)   55 (15)  
Median LDH level, U/L (range)  358 (57-6623)  
    Missing, no. of patients (%)   32 (9)  
Lymphadenopathy, no. of patients (%)  46 (13)  
    Missing   42 (12)  
Gum hypertrophy, no. of patients (%)  14 (4)  
    Missing   28 (8)  
Extramedullary involvement, no. of patients (%)  16 (4)  
    Missing
 
37 (10)
 

Subheadings under “De novo AML” refer to FAB subtypes. Percentages may not add to 100 because of rounding. MDS indicates myelodysplastic syndrome.

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