Cytokine production and AChE catalytic activity in LPS-injected TgR mice: inflammatory cytokine levels after LPS
. | TNFα (pg/mL) . | . | . | . | IL-6 (pg/mL) . | . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | Plasma, time after LPS . | . | BM, time after LPS . | . | Plasma, time after LPS . | . | BM, time after LPS . | . | ||||||
. | 0 h . | 2 h . | 0 h . | 2 h . | 0 h . | 2 h . | 0 h . | 2 h . | ||||||
| TgR mice | 0 | 834 ± 231 | 30 ± 4.2 | 120 ± 66 | 34 ± 2.5 | 1418 ± 62 | 35 ± 4.3 | 507 ± 135 | ||||||
| FVB/N mice | 0 | 538 ± 217 | 23 ± 8.3 | 334 ± 81 | 20 ± 4.5 | 1378 ± 40 | 8 ± 2.7 | 498 ± 331 | ||||||
| P | NS | .04 | NS | .01 | .01 | NS | .001 | NS | ||||||
. | TNFα (pg/mL) . | . | . | . | IL-6 (pg/mL) . | . | . | . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | Plasma, time after LPS . | . | BM, time after LPS . | . | Plasma, time after LPS . | . | BM, time after LPS . | . | ||||||
. | 0 h . | 2 h . | 0 h . | 2 h . | 0 h . | 2 h . | 0 h . | 2 h . | ||||||
| TgR mice | 0 | 834 ± 231 | 30 ± 4.2 | 120 ± 66 | 34 ± 2.5 | 1418 ± 62 | 35 ± 4.3 | 507 ± 135 | ||||||
| FVB/N mice | 0 | 538 ± 217 | 23 ± 8.3 | 334 ± 81 | 20 ± 4.5 | 1378 ± 40 | 8 ± 2.7 | 498 ± 331 | ||||||
| P | NS | .04 | NS | .01 | .01 | NS | .001 | NS | ||||||
TNFα and IL-6 levels were measured before and 2 hours after LPS injection. Data are expressed as means ± SD.
NS indicates not significant.