Microsatellite analysis of secondary epithelial cancers
. | . | . | Tetranucleotides . | . | . | . | . | . | Mononucleotides . | . | . | . | . | . | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | . | . | THO-1 . | . | SEE33 . | . | D14S120 . | . | BAT26 . | . | SRY . | . | ZP3 . | . | ||||||||||
| Patient ID . | Time after HCT, y . | Pathologic diagnosis . | Tumor . | Normal epith . | Tumor . | Normal epith . | Tumor . | Normal epith . | Tumor . | Normal epith . | Tumor . | Normal epith . | Tumor . | Normal epith . | ||||||||||
| C3 | 3.5 | Squamous Ca, tongue | MSI | MSI | NE | NE | MSI | NE | S | S | S | S | S | S | ||||||||||
| B16 | 2 | Squamous Ca, lip | MSI | S | MSI | MSI | MSI | NE | S | S | NA | NA | NE | NE | ||||||||||
| B24 | 10 | Squamous Ca, lip | MSI | MSI | MSI | NE | S | S | S | S | S | S | S | S | ||||||||||
. | . | . | Tetranucleotides . | . | . | . | . | . | Mononucleotides . | . | . | . | . | . | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | . | . | THO-1 . | . | SEE33 . | . | D14S120 . | . | BAT26 . | . | SRY . | . | ZP3 . | . | ||||||||||
| Patient ID . | Time after HCT, y . | Pathologic diagnosis . | Tumor . | Normal epith . | Tumor . | Normal epith . | Tumor . | Normal epith . | Tumor . | Normal epith . | Tumor . | Normal epith . | Tumor . | Normal epith . | ||||||||||
| C3 | 3.5 | Squamous Ca, tongue | MSI | MSI | NE | NE | MSI | NE | S | S | S | S | S | S | ||||||||||
| B16 | 2 | Squamous Ca, lip | MSI | S | MSI | MSI | MSI | NE | S | S | NA | NA | NE | NE | ||||||||||
| B24 | 10 | Squamous Ca, lip | MSI | MSI | MSI | NE | S | S | S | S | S | S | S | S | ||||||||||
Clinical data of the patients are shown in Tables 1 and 2. Tumor indicates that laser-microdissected tumor area was analyzed; noral epith, that laser-microdissected nonmalignant epithelium adjacent to the tumor area was analyzed.
HCT indicates hematopoietic cell transplantation; Ca, cancer; MSI, microsatellite instability; NE, not evaluable; S, stable microsatellites; NA, not applicable.