Donor-recipient relationships and histocompatibility in the HLA-mismatched group
. | . | Donor, no. (%) . | . | . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Variable . | Total, no. (%) . | Mother . | Father . | Sibling . | Offspring . | Cousin . | ||||
| Number | 135 (100) | 60 (44) | 21 (16) | 37 (27) | 13 (10) | 4 (3) | ||||
| HLA-antigen class mismatched | ||||||||||
| Class I | 32 (24) | 10 (17) | 10 (48) | 9 (24) | 1 (8) | 2 (50) | ||||
| Class II | 9 (7) | 4 (6) | 1 (4.8) | 4 (11) | 0 (0) | 0 (0) | ||||
| Classes I and II | 94 (70) | 46 (77) | 10 (48) | 24 (65) | 12 (92) | 2 (50) | ||||
| No. of HLA-antigen mismatched | ||||||||||
| 1 Ag | 21 (16) | 7 (12) | 4 (19) | 8 (22) | 1 (8) | 1 (25) | ||||
| 2 Ag | 62 (46) | 24 (40) | 15 (71) | 17 (46) | 3 (23) | 3 (75) | ||||
| 3 Ag | 52 (39) | 29 (48) | 2 (10) | 12 (32) | 9 (69) | 0 (0) | ||||
| No. and location of mismatched loci | ||||||||||
| Only at HLA-A | 6 (4) | 1 (2) | 3 (14) | 1 (3) | 0 (0) | 1 (25) | ||||
| Only at HLA-B | 6 (4) | 2 (3) | 0 (0) | 3 (8) | 1 (8) | 0 (0) | ||||
| Only at HLA-DRB1 | 9 (7) | 4 (7) | 1 (4) | 4 (11) | 0 (0) | 0 (0) | ||||
| Mismatches at HLA-A, -B | 20 (15) | 7 (12) | 7 (33) | 5 (14) | 0 (0) | 1 (25) | ||||
| Mismatches at HLA-A, -DRB1 | 11 (8) | 2 (3) | 2 (10) | 7 (19) | 0 (0) | 0 (0) | ||||
| Mismatches at HLA-B, -DRB1 | 31 (23) | 15 (25) | 6 (29) | 5 (13) | 3 (23) | 2 (50) | ||||
| Mismatches at HLA-A, -B, and -DRB1 | 52 (39) | 29 (48) | 2 (10) | 12 (32) | 9 (69) | 0 (0) | ||||
. | . | Donor, no. (%) . | . | . | . | . | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Variable . | Total, no. (%) . | Mother . | Father . | Sibling . | Offspring . | Cousin . | ||||
| Number | 135 (100) | 60 (44) | 21 (16) | 37 (27) | 13 (10) | 4 (3) | ||||
| HLA-antigen class mismatched | ||||||||||
| Class I | 32 (24) | 10 (17) | 10 (48) | 9 (24) | 1 (8) | 2 (50) | ||||
| Class II | 9 (7) | 4 (6) | 1 (4.8) | 4 (11) | 0 (0) | 0 (0) | ||||
| Classes I and II | 94 (70) | 46 (77) | 10 (48) | 24 (65) | 12 (92) | 2 (50) | ||||
| No. of HLA-antigen mismatched | ||||||||||
| 1 Ag | 21 (16) | 7 (12) | 4 (19) | 8 (22) | 1 (8) | 1 (25) | ||||
| 2 Ag | 62 (46) | 24 (40) | 15 (71) | 17 (46) | 3 (23) | 3 (75) | ||||
| 3 Ag | 52 (39) | 29 (48) | 2 (10) | 12 (32) | 9 (69) | 0 (0) | ||||
| No. and location of mismatched loci | ||||||||||
| Only at HLA-A | 6 (4) | 1 (2) | 3 (14) | 1 (3) | 0 (0) | 1 (25) | ||||
| Only at HLA-B | 6 (4) | 2 (3) | 0 (0) | 3 (8) | 1 (8) | 0 (0) | ||||
| Only at HLA-DRB1 | 9 (7) | 4 (7) | 1 (4) | 4 (11) | 0 (0) | 0 (0) | ||||
| Mismatches at HLA-A, -B | 20 (15) | 7 (12) | 7 (33) | 5 (14) | 0 (0) | 1 (25) | ||||
| Mismatches at HLA-A, -DRB1 | 11 (8) | 2 (3) | 2 (10) | 7 (19) | 0 (0) | 0 (0) | ||||
| Mismatches at HLA-B, -DRB1 | 31 (23) | 15 (25) | 6 (29) | 5 (13) | 3 (23) | 2 (50) | ||||
| Mismatches at HLA-A, -B, and -DRB1 | 52 (39) | 29 (48) | 2 (10) | 12 (32) | 9 (69) | 0 (0) | ||||