Table 3. ABCG2 mRNA expression in plasma... | American Society of Hematology

Table 3.

ABCG2 mRNA expression in plasma cells from subjects enrolled in the MTV trial

		ABCG2 mRNA expression/cell*
Paired sample	n	Before HDC	During HDC	Relapse from HDC	P†
Before HDC versus during HDC
Dose level 1	6	29.3	48.2	NA	.56
Dose levels 2 to 5	20	118.4	232.5	NA	.033
Before HDC versus relapsed from HDC
Dose level 1	5	26.6	NA	17.6	.999
Dose levels 2 to 5	11	31.7	NA	117.1	.001

		ABCG2 mRNA expression/cell*
Paired sample	n	Before HDC	During HDC	Relapse from HDC	P†
Before HDC versus during HDC
Dose level 1	6	29.3	48.2	NA	.56
Dose levels 2 to 5	20	118.4	232.5	NA	.033
Before HDC versus relapsed from HDC
Dose level 1	5	26.6	NA	17.6	.999
Dose levels 2 to 5	11	31.7	NA	117.1	.001

The analyses presented are for paired samples only, that is, before + during and before + relapse.

NA indicates not applicable.

The expression of ABCG2 is normalized to that of GAPDH.

Wilcoxon signed rank test.