Days without a bleeding episode following prophylactic infusions
. | No. of bleeding-free days . | . | . | . | . | . | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Treatment . | Mean . | Median . | Minimum . | Maximum . | SD . | 95% CI . | |||||
| rFVIII 35 IU/kg | |||||||||||
| Standard | 7.2 | 7.0 | 5 | 11 | 1.7 | 6.1-8.3 | |||||
| PEGLip | 13.3 | 13.5 | 6.0 | 20.5* | 4.8 | 10.1-16.5 | |||||
| rFVIII 25 IU/kg | |||||||||||
| Standard | 5.9 | 6.5 | 3 | 8 | 1.7 | 4.8-7.0 | |||||
| PEGLip | 10.9 | 11.0 | 5.5* | 16 | 2.9 | 9.0-12.7 | |||||
. | No. of bleeding-free days . | . | . | . | . | . | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Treatment . | Mean . | Median . | Minimum . | Maximum . | SD . | 95% CI . | |||||
| rFVIII 35 IU/kg | |||||||||||
| Standard | 7.2 | 7.0 | 5 | 11 | 1.7 | 6.1-8.3 | |||||
| PEGLip | 13.3 | 13.5 | 6.0 | 20.5* | 4.8 | 10.1-16.5 | |||||
| rFVIII 25 IU/kg | |||||||||||
| Standard | 5.9 | 6.5 | 3 | 8 | 1.7 | 4.8-7.0 | |||||
| PEGLip | 10.9 | 11.0 | 5.5* | 16 | 2.9 | 9.0-12.7 | |||||
For patients treated with 35 IU/kg rFVIII, n = 11 for each group; with 25 IU/kg rFVIII, n = 12 for each group.
Mean of 2 infusions.