Patient demographics and characteristics
. | Dosing cohort, mean (SD) . | . | |
|---|---|---|---|
| Characteristic . | 35 IU/kg . | 25 IU/kg . | |
| No. of patients | 12 | 12 | |
| Age, y | 25.8 (7.3) | 26.9 (8.1) | |
| Weight, kg | 65.8 (12.1) | 65.7 (10.3) | |
| Height, cm | 177.3 (6.1) | 175.2 (6.3) | |
| Infusions during previous 90 days, n | 29.0 (5.4) | 31.7 (6.1) | |
| Period between bleeds (treatments), d | 3.7 (1.0) | 3.4 (0.9) | |
| Dose per bleed, IU rFVIII | 714 (303) | 530 (38) | |
. | Dosing cohort, mean (SD) . | . | |
|---|---|---|---|
| Characteristic . | 35 IU/kg . | 25 IU/kg . | |
| No. of patients | 12 | 12 | |
| Age, y | 25.8 (7.3) | 26.9 (8.1) | |
| Weight, kg | 65.8 (12.1) | 65.7 (10.3) | |
| Height, cm | 177.3 (6.1) | 175.2 (6.3) | |
| Infusions during previous 90 days, n | 29.0 (5.4) | 31.7 (6.1) | |
| Period between bleeds (treatments), d | 3.7 (1.0) | 3.4 (0.9) | |
| Dose per bleed, IU rFVIII | 714 (303) | 530 (38) | |