IC50 values of PI3K inhibitors on in vitro primary splenic B-cell proliferation measured at different time points following anti-IgM stimulation
. | In vitro IC50, μM . | . | . | ||
|---|---|---|---|---|---|
| Inhibitor . | 24 h . | 48 h . | 72 h . | ||
| IC87114 | 0.04 | 0.17 | 0.14 | ||
| LY294002 | 0.25 | 0.72 | 0.94 | ||
| AS-604850 | > 10 | > 10 | > 10 | ||
. | In vitro IC50, μM . | . | . | ||
|---|---|---|---|---|---|
| Inhibitor . | 24 h . | 48 h . | 72 h . | ||
| IC87114 | 0.04 | 0.17 | 0.14 | ||
| LY294002 | 0.25 | 0.72 | 0.94 | ||
| AS-604850 | > 10 | > 10 | > 10 | ||