Average complete blood count (CBC) in peripheral blood of mice receiving transplants with Un-BM, MSCV-BM, and TEL2-BM, at the moment of death of the TEL2-BM mice
. | UN-BM . | MSCV-BM . | TEL2-BM* . |
|---|---|---|---|
| Complete WBC count, × 109/L | 8.6 ± 3.6 | 10.3 ± 4.9 | 76 ± 35.32 |
| Neutrophil count, × 109/L | 1.48 ± 0.52 | 2.36 ± 0.87 | 14.7 ± 13.94 |
| Lymphocyte count, × 109/L | 4.99 ± 1.68 | 4.64 ± 1.6 | 15.3 ± 14.05† |
| Monocyte count, × 109/L | 0.55 ± 0.28 | 0.57 ± 0.39 | 3.2 ± 2.8 |
| Eosinophil count, × 109/L | 0.019 ± 0.008 | 0.013 ± 0.005 | 1.14 ± 0.96 |
| Basophil count, × 109/L | 0 | 0 | 0.23 ± 0.19 |
| MCH, pg | 13.42 ± 1.45 | 15.19 ± 1.31 | 17.9 ± 4.4 |
| RBC count, × 1012/L | 7.46 ± 0.71 | 7.6 ± 0.811 | 4.66 ± 1.65 |
| MCV, fL | 44.84 ± 3.14 | 49.23 ± 3.32 | 62.68 ± 14.29 |
| Platelet count, × 109/L | 1176 ± 68.63 | 1406 ± 204 | 1094 ± 303 |
| Hemoglobin level, g/L | 127 ± 17 | 130 ± 17 | 84 ± 14 |
. | UN-BM . | MSCV-BM . | TEL2-BM* . |
|---|---|---|---|
| Complete WBC count, × 109/L | 8.6 ± 3.6 | 10.3 ± 4.9 | 76 ± 35.32 |
| Neutrophil count, × 109/L | 1.48 ± 0.52 | 2.36 ± 0.87 | 14.7 ± 13.94 |
| Lymphocyte count, × 109/L | 4.99 ± 1.68 | 4.64 ± 1.6 | 15.3 ± 14.05† |
| Monocyte count, × 109/L | 0.55 ± 0.28 | 0.57 ± 0.39 | 3.2 ± 2.8 |
| Eosinophil count, × 109/L | 0.019 ± 0.008 | 0.013 ± 0.005 | 1.14 ± 0.96 |
| Basophil count, × 109/L | 0 | 0 | 0.23 ± 0.19 |
| MCH, pg | 13.42 ± 1.45 | 15.19 ± 1.31 | 17.9 ± 4.4 |
| RBC count, × 1012/L | 7.46 ± 0.71 | 7.6 ± 0.811 | 4.66 ± 1.65 |
| MCV, fL | 44.84 ± 3.14 | 49.23 ± 3.32 | 62.68 ± 14.29 |
| Platelet count, × 109/L | 1176 ± 68.63 | 1406 ± 204 | 1094 ± 303 |
| Hemoglobin level, g/L | 127 ± 17 | 130 ± 17 | 84 ± 14 |
The results are expressed as average ± SD. The 2-tail unpaired Student t test was used to compare the data. P ≤.05 was considered significant.
MCH indicates mean corpuscular hemoglobin; MCV, mean corpuscular volume.
P values calculated between the TEL2-BM and the MSCV-BM values were < .05
The high number of lymphocytes in the Hemavet counts of the TEL2-BM mouse blood samples is a gross overestimate because the blast cells and partially differentiated myeloid cells have the same size as lymphocytes and are therefore scored as “lymphocytes.” This was confirmed by morphologic analysis of the blood smears (Figure 2A)