BMT from NIMA-exposed donor favored immune reconstitution
. | . | CD4+ T cells, × 106 . | . | CD8+ T cells, × 106 . | . | ||
|---|---|---|---|---|---|---|---|
| Donor . | Host . | Average . | SE . | Average . | SE . | ||
| BDF1 | BDF1 | 6.53 | 0.65 | 3.24 | 0.35 | ||
| NIMA-B6 | BDF1 | 1.38* | 0.31 | 1.25* | 0.05 | ||
| Control-B6 | BDF1 | 0.16 | 0.03 | 0.12 | 0.03 | ||
. | . | CD4+ T cells, × 106 . | . | CD8+ T cells, × 106 . | . | ||
|---|---|---|---|---|---|---|---|
| Donor . | Host . | Average . | SE . | Average . | SE . | ||
| BDF1 | BDF1 | 6.53 | 0.65 | 3.24 | 0.35 | ||
| NIMA-B6 | BDF1 | 1.38* | 0.31 | 1.25* | 0.05 | ||
| Control-B6 | BDF1 | 0.16 | 0.03 | 0.12 | 0.03 | ||
B6D2F1 mice were irradiated with 13 Gy TBI and received transplants with 5 × 106 TCD BM cells from control B6 mice together with 2 × 106 T cells from either a NIMA donor or a control donor. The numbers of CD4+ and CD8+ T cells in spleen 40 days after BMT are shown.
SE indicates standard error.
P < .05 versus controls