Table 3.

Analysis of multipotent progenitors of Lyl-1-/- mice by CFU-S12 assays



No. CFU-S12/5 × 104 cells
Genotype
BM
E14 FL
Lyl-1+/+  14.5 ± 0.9*  7.2 ± 0.7* 
Lyl-1-/-
 
10.2 ± 1.1
 
4.7 ± 0.6
 


No. CFU-S12/5 × 104 cells
Genotype
BM
E14 FL
Lyl-1+/+  14.5 ± 0.9*  7.2 ± 0.7* 
Lyl-1-/-
 
10.2 ± 1.1
 
4.7 ± 0.6
 

BM or E14 FL cells (5 × 104) were injected into irradiated recipients. Mice were killed at 12 days, and spleen colonies were macroscopically counted. Values are mean ± SEM from 5 independent experiments.

*

P < .05.

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