In vivo effect of anti-CD11b in infected mice
. | Parasites/105 cells . | P . |
|---|---|---|
| MLN | ||
| Control | 1.2 × 104 ± 1.3 × 103 | .004* |
| Anti-CD11b | 5.8 × 103 ± 4.6 × 102 | |
| Blood | ||
| Control | 215.4 ± 160.9 | .437 (NS) |
| Anti-CD11b | 98.7 ± 171 | |
| Brain | ||
| Control | 1066.2 ± 97.8 | .003* |
| Anti-CD11b | 520.4 ± 111 |
. | Parasites/105 cells . | P . |
|---|---|---|
| MLN | ||
| Control | 1.2 × 104 ± 1.3 × 103 | .004* |
| Anti-CD11b | 5.8 × 103 ± 4.6 × 102 | |
| Blood | ||
| Control | 215.4 ± 160.9 | .437 (NS) |
| Anti-CD11b | 98.7 ± 171 | |
| Brain | ||
| Control | 1066.2 ± 97.8 | .003* |
| Anti-CD11b | 520.4 ± 111 |
Parasite loads were estimated by quantitative PCR at day 8 after intragastric delivery of 20 T gondii cysts and following the IV administration in B6 mice of anti-CD11b or of irrelevant mAb (Control) at day 6 and day 7 after inoculation. Values are tested using a Student t test.
NS indicates not significant.
Indicates significant at 0.1% threshold