Table 3.

Univariate analyses of progression-free survival





95% CI for HR
Characteristic
P
HR
Lower
Upper
Age at diagnosis   .953   0.999   0.969   1.030  
Sex   .980   1.012   0.391   26.17  
Clinical stage, I-IV   < .001   2.954   1.658   5.262  
Number of involved regions   .014   1.272   1.050   1.541  
Extranodal involvement   < .001   7.723   3.021   19.742  
B-symptoms   .024   3.592   1.182   10.92  
Bulky disease   .261   1.704   0.672   4.320  
Histologic subtype   .701   –   –   –  
Albumin, g/L   .033   0.926   0.863   0.994  
Sedimentation rate, WU   .609   1.003   0.991   1.016  
Hemoglobin, mM   .164   0.794   0.573   1.099  
Leukocyte count, × 109/L   .024   1.149   1.019   1.297  
Lymphocyte count, × 109/L   .161   0.583   0.273   1.241  
IPS   .011   1.837   1.147   2.944  
Early interim PET, qualitative   < .001   43.82   9.213   208.4  
Early interim PET, SUVmax
 
< .001
 
1.131
 
1.054
 
1.214
 




95% CI for HR
Characteristic
P
HR
Lower
Upper
Age at diagnosis   .953   0.999   0.969   1.030  
Sex   .980   1.012   0.391   26.17  
Clinical stage, I-IV   < .001   2.954   1.658   5.262  
Number of involved regions   .014   1.272   1.050   1.541  
Extranodal involvement   < .001   7.723   3.021   19.742  
B-symptoms   .024   3.592   1.182   10.92  
Bulky disease   .261   1.704   0.672   4.320  
Histologic subtype   .701   –   –   –  
Albumin, g/L   .033   0.926   0.863   0.994  
Sedimentation rate, WU   .609   1.003   0.991   1.016  
Hemoglobin, mM   .164   0.794   0.573   1.099  
Leukocyte count, × 109/L   .024   1.149   1.019   1.297  
Lymphocyte count, × 109/L   .161   0.583   0.273   1.241  
IPS   .011   1.837   1.147   2.944  
Early interim PET, qualitative   < .001   43.82   9.213   208.4  
Early interim PET, SUVmax
 
< .001
 
1.131
 
1.054
 
1.214
 

P indicates level of significance; HR, hazard ratio; CI, confidence interval; –, not applicable; and WU, working unit.

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