Table 4. Results of studies in high-risk... | American Society of Hematology

Table 4.

Results of studies in high-risk MM patients and of tandem ASCT

Study in high-risk MM patients	Criteria	No. patients	Median EFS, mo	Median OS, mo
IFM⁷	β₂-m ≥ 2.5 and Δ13^*	22/168	15†	25
Arkansas¹⁴	β₂-m > 4 and Δ11/13‡	23/229	20.4	25.2
Arkansas¹⁵	β₂-m > 2.5 and Δ13/hypodiploid‡ and albumin <35	317/1475	11	16
IFM 99-04	β₂-m > 3 and Δ13	219	30	41
Tandem ASCT
IFM 94⁴	de novo, < 61 y	200	30	58
MAG 95¹⁶	de novo, < 59 y	115	33	73
Bologna¹⁷	de novo, < 61 y	113	31	60

Study in high-risk MM patients	Criteria	No. patients	Median EFS, mo	Median OS, mo
IFM⁷	β₂-m ≥ 2.5 and Δ13^*	22/168	15†	25
Arkansas¹⁴	β₂-m > 4 and Δ11/13‡	23/229	20.4	25.2
Arkansas¹⁵	β₂-m > 2.5 and Δ13/hypodiploid‡ and albumin <35	317/1475	11	16
IFM 99-04	β₂-m > 3 and Δ13	219	30	41
Tandem ASCT
IFM 94⁴	de novo, < 61 y	200	30	58
MAG 95¹⁶	de novo, < 59 y	115	33	73
Bologna¹⁷	de novo, < 61 y	113	31	60

FISH analysis

Progression-free survival

Conventional cytogenetic