Toxicity of the second conditioning regimen
. | Arm A; n = 85 . | Arm B; n = 81 . | P . |
|---|---|---|---|
| Duration of G-CSF, d, range (median) | 4-13 (6) | 2-11 (6) | .70 |
| Duration of neutropenia, d, range (median) | 4-15 (8) | 4-19 (7) | .88 |
| Duration of thrombocytopenia, d, range (median) | 2-100 (8) | 0-200 (8) | .71 |
| No. of platelet transfusions, range (median) | 0-8 | 0-29 | .63 |
| No. of red blood cell transfusions, range (median) | 0-10 (1) | 0-9 (2) | .45 |
| Duration of hospitalization, d, range (median) | 17-120 (22) | 13-82 (22) | .68 |
| Anti–IL-6 toxicity | – | 0 | – |
| Cardiac toxicity grades III-IV, no. (%) | 1 (1.2) | 2 (2.5) | .61 |
| Mucositis grades III-IV, no. (%) | 46 (54.1) | 40 (49.4) | .64 |
| Pulmonary toxicity grades III-IV, no. (%) | 3 (3.5) | 3 (3.7) | > .99 |
| Renal toxicity grades III-IV, no. (%) | 3 (3.5) | 2 (2.5) | > .99 |
| Liver toxicity grades III-IV, no. (%) | 2 (2.4) | 2 (2.5) | > .99 |
| Toxic death, no. (%) | 1 (1.2) | 2 (2.5) | .61 |
. | Arm A; n = 85 . | Arm B; n = 81 . | P . |
|---|---|---|---|
| Duration of G-CSF, d, range (median) | 4-13 (6) | 2-11 (6) | .70 |
| Duration of neutropenia, d, range (median) | 4-15 (8) | 4-19 (7) | .88 |
| Duration of thrombocytopenia, d, range (median) | 2-100 (8) | 0-200 (8) | .71 |
| No. of platelet transfusions, range (median) | 0-8 | 0-29 | .63 |
| No. of red blood cell transfusions, range (median) | 0-10 (1) | 0-9 (2) | .45 |
| Duration of hospitalization, d, range (median) | 17-120 (22) | 13-82 (22) | .68 |
| Anti–IL-6 toxicity | – | 0 | – |
| Cardiac toxicity grades III-IV, no. (%) | 1 (1.2) | 2 (2.5) | .61 |
| Mucositis grades III-IV, no. (%) | 46 (54.1) | 40 (49.4) | .64 |
| Pulmonary toxicity grades III-IV, no. (%) | 3 (3.5) | 3 (3.7) | > .99 |
| Renal toxicity grades III-IV, no. (%) | 3 (3.5) | 2 (2.5) | > .99 |
| Liver toxicity grades III-IV, no. (%) | 2 (2.4) | 2 (2.5) | > .99 |
| Toxic death, no. (%) | 1 (1.2) | 2 (2.5) | .61 |
– indicates not applicable.