Risk assessment for persistence or recurrence of venous thrombosis in children
Patient characteristics |
| Low risk |
| Trigger resolved/removed |
| Transient underlying medical condition |
| Standard risk |
| FVIII level 150 U/dL or less |
| D-dimer level 500 ng/mL or less |
| Fewer than 3 trait thrombophilias* |
| High risk |
| FVIII level greater than 150 U/dL |
| D-dimer level greater than 500 ng/mL |
| At least 3 trait thrombophilias* |
| Persistent antiphospholipid antibody |
| Thrombus characteristics |
| Low risk |
| Resolved within 6 weeks |
| Standard risk |
| Atrial |
| Nonocclusive DVT |
| High risk |
| Vena cava |
| Occlusive DVT |
Patient characteristics |
| Low risk |
| Trigger resolved/removed |
| Transient underlying medical condition |
| Standard risk |
| FVIII level 150 U/dL or less |
| D-dimer level 500 ng/mL or less |
| Fewer than 3 trait thrombophilias* |
| High risk |
| FVIII level greater than 150 U/dL |
| D-dimer level greater than 500 ng/mL |
| At least 3 trait thrombophilias* |
| Persistent antiphospholipid antibody |
| Thrombus characteristics |
| Low risk |
| Resolved within 6 weeks |
| Standard risk |
| Atrial |
| Nonocclusive DVT |
| High risk |
| Vena cava |
| Occlusive DVT |
Thrombophilias include genetic and acquired prothrombotic traits that can be determined in blood and are listed in Table 3