Table 1. Gene expression changes in... | American Society of Hematology

Table 1.

Gene expression changes in 32DWT1 cells treated with ZnCl₂

Gene	UniGene no.	Fold change with ZnCl₂
Caveolin 2	Mm.31915	0.15
Dffa	Mm.41433	0.26
Pdcd11	Mm.41166	0.32
CIDE-A	Mm.449	0.36
RBBP4	Mm.12145	2.67
IGF-II	Mm.3862	2.96
PTEN	Mm.220979	3.33
Cyclin A2	Mm.4189	4.2
14-3-3 η	Mm.332314	4.22
Sfrp5	Mm.103731	4.55
PCNA	Mm.7141	5.02
CDK4	Mm.6839	6.23
Granzyme B	Mm.14874	10.72
NAIP	Mm.89961	11.2
ODC	Mm.34102	16.95
CBP	Mm.132238	17.53
MT-2	Mm.147226	39
Granzyme A	Mm.15510	—
Sfrp2	Mm.19155	—
BID	Mm.235081	—
A1	Mm.196770	—
CDK6	Mm.31672	—
Thrombospondin	Mm.4159	—
APEX	Mm.203	—

Gene	UniGene no.	Fold change with ZnCl₂
Caveolin 2	Mm.31915	0.15
Dffa	Mm.41433	0.26
Pdcd11	Mm.41166	0.32
CIDE-A	Mm.449	0.36
RBBP4	Mm.12145	2.67
IGF-II	Mm.3862	2.96
PTEN	Mm.220979	3.33
Cyclin A2	Mm.4189	4.2
14-3-3 η	Mm.332314	4.22
Sfrp5	Mm.103731	4.55
PCNA	Mm.7141	5.02
CDK4	Mm.6839	6.23
Granzyme B	Mm.14874	10.72
NAIP	Mm.89961	11.2
ODC	Mm.34102	16.95
CBP	Mm.132238	17.53
MT-2	Mm.147226	39
Granzyme A	Mm.15510	—
Sfrp2	Mm.19155	—
BID	Mm.235081	—
A1	Mm.196770	—
CDK6	Mm.31672	—
Thrombospondin	Mm.4159	—
APEX	Mm.203	—

Listed are genes noted to be significantly up- or down-regulated upon WT1 induction in 32DWT1 cells, but not (with the exception of metallothionein) in 32DV4 cells treated with ZnCl₂. Metallothionein was up-regulated in control cells, which is the expected response to treatment with heavy metal.

— indicates a gene that was expressed only after treatment with ZnCl₂.

View Large

This Feature Is Available To Subscribers Only