Retrospective studies of ARL outcomes before and after HAART
. | . | HAART, no. . | . | CR, %, HAART . | . | . | Median OS, mo, HAART . | . | . | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reference . | Type and comments . | No . | Yes . | No . | Yes . | P . | No . | Yes . | P . | |||||
Vaccher et al15 | HAART: more neuropathy, anemia, fewer Ols | 80 | 24 | 36 | 50 | NS | 7 | NR | – | |||||
Navarro et al16 | CHOP regimen, all systemic ARL in this series; 2 yr OS (previous report): 60% vs 22% | 54 | 39 | 39 | 60 | .019 | NR | NR | – | |||||
Hoffmann et al17 | CHOP regimen; HAART response associated with much better OS | 142 | 61 | 48 | 71 | .006 | 9 | NR | – | |||||
Besson et al7 | Mostly CHOP-like regimens; higher CD4 count at diagnosis after HAART | 63 | 42 | NR | NR | 6.3 | 21.2 | .004 | ||||||
Gerard et al14 | Half of patients treated with intensive regimens; after HAART, fewer received dose-reduced regimens | 131 | 115 | 55 | 69 | .04 | 9.5 | NR | < .001 |
. | . | HAART, no. . | . | CR, %, HAART . | . | . | Median OS, mo, HAART . | . | . | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reference . | Type and comments . | No . | Yes . | No . | Yes . | P . | No . | Yes . | P . | |||||
Vaccher et al15 | HAART: more neuropathy, anemia, fewer Ols | 80 | 24 | 36 | 50 | NS | 7 | NR | – | |||||
Navarro et al16 | CHOP regimen, all systemic ARL in this series; 2 yr OS (previous report): 60% vs 22% | 54 | 39 | 39 | 60 | .019 | NR | NR | – | |||||
Hoffmann et al17 | CHOP regimen; HAART response associated with much better OS | 142 | 61 | 48 | 71 | .006 | 9 | NR | – | |||||
Besson et al7 | Mostly CHOP-like regimens; higher CD4 count at diagnosis after HAART | 63 | 42 | NR | NR | 6.3 | 21.2 | .004 | ||||||
Gerard et al14 | Half of patients treated with intensive regimens; after HAART, fewer received dose-reduced regimens | 131 | 115 | 55 | 69 | .04 | 9.5 | NR | < .001 |
NS indicates not significant; NR, not reported; and –, not calculated.