Table 3. Regions of genomic alterations... | American Society of Hematology

Table 3.

Regions of genomic alterations characteristic of acute or lymphoma types

Chromosome band*	Megabases	Acute type†	Lymphoma type†
Gain
1q22-23.1	3	0	11
1q41-44	29.3	0	12-17
2p25	3.1	0	10-13
3p26.3-q26.2	0.2-170.85	6-11‡	4-14
4q21.1-22.1	76.5-92.2	0	10-12
4q26-27	115.7-120.3	0	10-12
7p22.2-22.3	0.5-3.7	0	10-13
7q11.23-7q36.3	76.2-156.9	0-1	15-28
Loss
10p12.31-12.1	20-28.3	0-1	11-15
13q21.1-q32.1	49.45-91	0-1	10-20
16q21-q22.2	9.6-73.1	0	10-13
18p11.22	8.7-10.1	0	12

Chromosome band*	Megabases	Acute type†	Lymphoma type†
Gain
1q22-23.1	3	0	11
1q41-44	29.3	0	12-17
2p25	3.1	0	10-13
3p26.3-q26.2	0.2-170.85	6-11‡	4-14
4q21.1-22.1	76.5-92.2	0	10-12
4q26-27	115.7-120.3	0	10-12
7p22.2-22.3	0.5-3.7	0	10-13
7q11.23-7q36.3	76.2-156.9	0-1	15-28
Loss
10p12.31-12.1	20-28.3	0-1	11-15
13q21.1-q32.1	49.45-91	0-1	10-20
16q21-q22.2	9.6-73.1	0	10-13
18p11.22	8.7-10.1	0	12

For acute-type ATLL, n = 17; for lymphoma-type ATLL, n = 49.

Regions are listed that showed significant differences in frequency between acute and lymphoma types.

Number of cases with genomic alterations.

Characteristic region of acute type.