Characteristics of ATLL patients and their clinical features based on diagnostic criteria (n = 66)
Characteristic . | Acute type . | Lymphoma type . |
|---|---|---|
| No. of patients | 17 | 49 |
| Median age, y (range) | 57 (44-78) | 64 (36-85) |
| Sex, no. male (%) | 9 (53) | 26 (53) |
| Performance status, no. (%) | ||
| 0-2 | 8 (47) | ND |
| Greater than 2 | 9 (53) | ND |
| Nodal involvement, no. (%) | 7 (41) | 49 (100) |
| Hepatosplenomegaly, no. (%) | 6 (35) | ND |
| Cell type* | Peripheral blood | Lymph node |
| Flower cells† | + | - |
| Elevated WBC count‡, no. (%) | 17 (100) | ND |
| LDH level, no. (%) | ||
| Normal | 1 (6) | ND |
| Elevated | 16 (94) | ND |
| Ca level, no. (%) | ||
| Normal | 8 (47) | ND |
| Elevated | 9 (53) | ND |
Characteristic . | Acute type . | Lymphoma type . |
|---|---|---|
| No. of patients | 17 | 49 |
| Median age, y (range) | 57 (44-78) | 64 (36-85) |
| Sex, no. male (%) | 9 (53) | 26 (53) |
| Performance status, no. (%) | ||
| 0-2 | 8 (47) | ND |
| Greater than 2 | 9 (53) | ND |
| Nodal involvement, no. (%) | 7 (41) | 49 (100) |
| Hepatosplenomegaly, no. (%) | 6 (35) | ND |
| Cell type* | Peripheral blood | Lymph node |
| Flower cells† | + | - |
| Elevated WBC count‡, no. (%) | 17 (100) | ND |
| LDH level, no. (%) | ||
| Normal | 1 (6) | ND |
| Elevated | 16 (94) | ND |
| Ca level, no. (%) | ||
| Normal | 8 (47) | ND |
| Elevated | 9 (53) | ND |
ND indicates not determined; +, present; -, absent.
Cell types from which the DNA was extracted: peripheral blood for acute type and lymph node for lymphoma type.
Flower cells were observed in peripheral blood in all patients with acute-type ATLL, and in none of the patients with lymphoma-type ATLL.
Elevated WBC count defined as more than 10 × 109/L (10 000/μL).