Patient characteristics
Patient . | Age, y/sex . | Prior Rx . | WBC/ANC, × 109/L . | Hgb level, g/dL . | Platelet count, × 109/L . | Size of spleen/nodes, cm . | IgVH homology, % . | P53 deletion/monosomy 17 by FISH . |
|---|---|---|---|---|---|---|---|---|
| 1 | 54/F | 2CDA | 2.6/0.78 | 13.1 | 105 | 0/0 | 97.9 | Negative |
| 2 | 32/M | None | 5.7/1.82 | 13.1 | 55 | 0/0 | NA | Negative |
| 3 | 54/M | None | 2.2/1.23 | 13.9 | 113 | 3/1.5 | NA | Negative |
| 4 | 47/F | None | 2.7/0.68 | 9.1 | 38 | 0/0 | 95 | Positive |
| 5* | 69/M | Chl | 72.8/0.0 | 12.6 | 140 | 0/2 | 100 | Positive |
| 6 | 53/F | None | 1.5/0.69 | 10.3 | 51 | 3/0 | NA | Negative |
| 7 | 67/F | None | 2.0/0.68 | 12.2 | 76 | 0/0 | 95.1 | Negative |
| 8* | 74/F | None | 31.6/2.53 | 13.3 | 275 | 0/0 | 100 | Negative |
| 9 | 60/M | None | 0.9/0.04 | 7.8 | 46 | 0/0 | 95.6 | Negative |
| 10 | 58/M | None | 2.4/0.65 | 10.1 | 80 | 0/0 | 98 | Negative |
| 11 | 52/F | None | 4.1/0.94 | 13.6 | 60 | 0/0 | 97.6 | Negative |
| 12 | 58/M | None | 4.1/0.98 | 12.9 | 86 | 0/0 | 98.7 | Negative |
| 13 | 47/M | None | 5.0/2.1 | 15.6 | 54 | 7/0 | 96.6 | Negative |
Patient . | Age, y/sex . | Prior Rx . | WBC/ANC, × 109/L . | Hgb level, g/dL . | Platelet count, × 109/L . | Size of spleen/nodes, cm . | IgVH homology, % . | P53 deletion/monosomy 17 by FISH . |
|---|---|---|---|---|---|---|---|---|
| 1 | 54/F | 2CDA | 2.6/0.78 | 13.1 | 105 | 0/0 | 97.9 | Negative |
| 2 | 32/M | None | 5.7/1.82 | 13.1 | 55 | 0/0 | NA | Negative |
| 3 | 54/M | None | 2.2/1.23 | 13.9 | 113 | 3/1.5 | NA | Negative |
| 4 | 47/F | None | 2.7/0.68 | 9.1 | 38 | 0/0 | 95 | Positive |
| 5* | 69/M | Chl | 72.8/0.0 | 12.6 | 140 | 0/2 | 100 | Positive |
| 6 | 53/F | None | 1.5/0.69 | 10.3 | 51 | 3/0 | NA | Negative |
| 7 | 67/F | None | 2.0/0.68 | 12.2 | 76 | 0/0 | 95.1 | Negative |
| 8* | 74/F | None | 31.6/2.53 | 13.3 | 275 | 0/0 | 100 | Negative |
| 9 | 60/M | None | 0.9/0.04 | 7.8 | 46 | 0/0 | 95.6 | Negative |
| 10 | 58/M | None | 2.4/0.65 | 10.1 | 80 | 0/0 | 98 | Negative |
| 11 | 52/F | None | 4.1/0.94 | 13.6 | 60 | 0/0 | 97.6 | Negative |
| 12 | 58/M | None | 4.1/0.98 | 12.9 | 86 | 0/0 | 98.7 | Negative |
| 13 | 47/M | None | 5.0/2.1 | 15.6 | 54 | 7/0 | 96.6 | Negative |
Rx indicates medication; WBC, white blood count; ANC, absolute neutrophil count; Hgb, hemoglobin; FISH, fluorescent in situ hybridization; 2CDA, 2-chlorodeoxyadenosine; NA, not available; Chl, chlorambucil.
Variant HCL.