The B-cell essential CBP and p300 interactome
Common name and reference . | Mouse gene symbol . | Essential for B cells or B and T cells in mice, MGI . |
|---|---|---|
| 53BP16 | Trp53bp1 | B and T cells |
| A-Myb7 | Mybl1 | B cells |
| BCL68 | Bcl6 | B and T cells |
| C/EBPβ9 | Cebpb | B and T cells |
| CIITA9 | C2ta | B and T cells |
| c-Jun10 | Jun | B and T cells |
| c-Myb10 | Myb | B and T cells |
| c-Myc11 | Myc | B cells |
| E4712 | Tcfe2a | B and T cells |
| EBF13 | Ebf1 | B cells |
| Ets-114 | Ets1 | B and T cells |
| GATA-215 | Gata2 | B and T cells |
| HEB16 | Tcf12 | B cells |
| HIF-1α10 | Hif1a | B cells |
| Hoxa917 | Hoxa9 | B and T cells |
| IRF-218 | Irf2 | B and T cells |
| MDM29 | Mdm2 | B and T cells |
| Msh26 | Msh2 | B and T cells |
| Msh66 | Msh6 | B and T cells |
| NBS16 | Nbn | B cells |
| NFAT119 | Nfatc2 | B and T cells |
| NFATc120 | Nfatc1 | B and T cells |
| NF-κB p5021 | Nfkb1 | B and T cells |
| NF-κB p659 | Rela | B and T cells |
| Pax522 | Pax5 | B cells |
| PML23 | Pml | B and T cells |
| PPARγ24 | Pparg | B cells |
| PU.115 | Sfpi1 | B and T cells |
| Rad506 | Rad50 | B and T cells |
| Runx225 | Runx2 | B and T cells |
| Smad310 | Smad3 | B and T cells |
| Sp326 | Sp3 | B and T cells |
| Spi-B27 | Spib | B cells |
| STAT1α10 | Stat1 | B and T cells |
| STAT628 | Stat6 | B and T cells |
| TCF-4N29 | Tcf4 | B and T cells |
Common name and reference . | Mouse gene symbol . | Essential for B cells or B and T cells in mice, MGI . |
|---|---|---|
| 53BP16 | Trp53bp1 | B and T cells |
| A-Myb7 | Mybl1 | B cells |
| BCL68 | Bcl6 | B and T cells |
| C/EBPβ9 | Cebpb | B and T cells |
| CIITA9 | C2ta | B and T cells |
| c-Jun10 | Jun | B and T cells |
| c-Myb10 | Myb | B and T cells |
| c-Myc11 | Myc | B cells |
| E4712 | Tcfe2a | B and T cells |
| EBF13 | Ebf1 | B cells |
| Ets-114 | Ets1 | B and T cells |
| GATA-215 | Gata2 | B and T cells |
| HEB16 | Tcf12 | B cells |
| HIF-1α10 | Hif1a | B cells |
| Hoxa917 | Hoxa9 | B and T cells |
| IRF-218 | Irf2 | B and T cells |
| MDM29 | Mdm2 | B and T cells |
| Msh26 | Msh2 | B and T cells |
| Msh66 | Msh6 | B and T cells |
| NBS16 | Nbn | B cells |
| NFAT119 | Nfatc2 | B and T cells |
| NFATc120 | Nfatc1 | B and T cells |
| NF-κB p5021 | Nfkb1 | B and T cells |
| NF-κB p659 | Rela | B and T cells |
| Pax522 | Pax5 | B cells |
| PML23 | Pml | B and T cells |
| PPARγ24 | Pparg | B cells |
| PU.115 | Sfpi1 | B and T cells |
| Rad506 | Rad50 | B and T cells |
| Runx225 | Runx2 | B and T cells |
| Smad310 | Smad3 | B and T cells |
| Sp326 | Sp3 | B and T cells |
| Spi-B27 | Spib | B cells |
| STAT1α10 | Stat1 | B and T cells |
| STAT628 | Stat6 | B and T cells |
| TCF-4N29 | Tcf4 | B and T cells |
Thirty-six mammalian proteins that interact physically or functionally with CBP or p300 in vitro and which are encoded by genes that are essential for B cells in mice (ie, mutation results in a B-cell or combined T- and B-cell phenotype). Source for phenotype information is Mouse Genome Informatics (MGI).30 More detailed and up-to-date information on the entire CBP/p300 interactome can be found at http://www.stjude.org/faculty/0,2081,407_2030_20103,00.html.5