Table 2. Cell division of... | American Society of Hematology

Table 2.

Cell division of antigen-specific (HIV and CMV) CD8⁺ T cells

Subject	6 hours	48 hours	No division	Division	% CD57⁺	% CCR7⁺	% CD28⁺	% CD27⁺
24	3.5	2.5	1.9	0.7	61	15	65	72
6	6.5	3.9	2.3	1.6	44	6	56	81
4	3.8	2.8	1.8	1.0	43	15	51	72
7	2.6	0.5	0.3	0.3	70	8.5	45	43
12	3.4	1.5	1.2	0.3	60	5	48	43
17	6.3	0.2	0.1	0.1	76	7	45	76
14	4.8	5.0	2.9	2.1	33	14	54	91
15	4.7	9.8	3.6	6.2	18	12	68	87
16	7.5	1.4	0.9	0.4	56	9.5	42	44
27	2.6	1.2	0.7	0.5	55	8	35	77
13	2.1	0.6	0.6	0	77	3	45	61
31	27.4	25	11.4	13.4	21	19	76	93
R²	—	—	—	—	0.90	0.28	0.48	0.33

Subject	6 hours	48 hours	No division	Division	% CD57⁺	% CCR7⁺	% CD28⁺	% CD27⁺
24	3.5	2.5	1.9	0.7	61	15	65	72
6	6.5	3.9	2.3	1.6	44	6	56	81
4	3.8	2.8	1.8	1.0	43	15	51	72
7	2.6	0.5	0.3	0.3	70	8.5	45	43
12	3.4	1.5	1.2	0.3	60	5	48	43
17	6.3	0.2	0.1	0.1	76	7	45	76
14	4.8	5.0	2.9	2.1	33	14	54	91
15	4.7	9.8	3.6	6.2	18	12	68	87
16	7.5	1.4	0.9	0.4	56	9.5	42	44
27	2.6	1.2	0.7	0.5	55	8	35	77
13	2.1	0.6	0.6	0	77	3	45	61
31	27.4	25	11.4	13.4	21	19	76	93
R²	—	—	—	—	0.90	0.28	0.48	0.33

Values are listed as a percentage of total CD8⁺ T cells that produced IFN-γ after 6 hours and 48 hours, and IFN-γ–producing cells that had or had not divided after 48 hours (columns 2-5). Percentages of antigen-specific CD8⁺ T cells that express listed surface molecules are also shown (columns 6-9). R² describes correlation based on linear regression between expression of individual surface molecules with the percentage of those CD8⁺ T cells that proliferated in response to antigenic stimulation (last row).

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