Table 4.

Multivariate analysis of disease-free survival

VariablesRelative risk of treatment failure
(95% confidence interval)
P
HLA-identical sibling transplant
versus autologous transplant 
  
 First 6 mo after transplantation 1.49 (0.92-2.40) .10 
 Beyond 6 mo after transplantation 0.58 (0.27-1.22) .15 
Other significant variables   
 Disease status at transplantation4-150   
  CR1 1.00  
  CR2 or more 1.82 (1.03-3.22) .04  
  Relapse 1 or more 3.17 (1.69-5.32) < .0001  
  Primary induction failure 2.65 (1.55-4.53) .0004 
VariablesRelative risk of treatment failure
(95% confidence interval)
P
HLA-identical sibling transplant
versus autologous transplant 
  
 First 6 mo after transplantation 1.49 (0.92-2.40) .10 
 Beyond 6 mo after transplantation 0.58 (0.27-1.22) .15 
Other significant variables   
 Disease status at transplantation4-150   
  CR1 1.00  
  CR2 or more 1.82 (1.03-3.22) .04  
  Relapse 1 or more 3.17 (1.69-5.32) < .0001  
  Primary induction failure 2.65 (1.55-4.53) .0004 

CR indicates complete remission; and RR, relative risk.

F4-150

≥ Relapse 1 versus ≥ CR2, RR, 1.74 (95% CI, 1.00-3.03),P = .05; primary induction failure versus ≥ CR2, RR, 1.46 (95% CI, 0.82-2.58), P = .20; primary induction failure versus ≥ relapse 1, RR, 0.84 (95% CI, 0.50-1.40), P = 0.49.

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