Table 2. Bone marrow counts of leukemic... | American Society of Hematology

Table 2.

Bone marrow counts of leukemic FLT3^W51/PML-RARα mice

Mice	Imm/Bl	Intermediate	Neutrophils	Erythrocytes	Lymphocytes	Eosinophils	Other
Control	2.8	15.7	25.6	39.9	13.7	2.6	0
PML-RARα leukemia	81.3	4.5	0.7	8.7	4.6	0.3	0
PML-RARα/FLT3^W51leukemia	68.5	7.0	4.2	12.8	3.8	0.9	2.5
874	85.8	4	1.5	0	2.5	2.8	4.3
1019	64.5	13	11.5	4.8	2	2	3.5
1020	75.8	7.5	1.5	4.3	8.8	0	2.3
1086	50.8	2.3	0.5	36	4.5	0.8	2.3
1087	66.3	8.3	4.5	15.8	2.5	0.25	0.5
1127	65.5	10.3	9.3	10.5	3.3	0.3	0.5
1128	70.8	3.3	0.8	18	2.8	0.3	4

Mice	Imm/Bl	Intermediate	Neutrophils	Erythrocytes	Lymphocytes	Eosinophils	Other
Control	2.8	15.7	25.6	39.9	13.7	2.6	0
PML-RARα leukemia	81.3	4.5	0.7	8.7	4.6	0.3	0
PML-RARα/FLT3^W51leukemia	68.5	7.0	4.2	12.8	3.8	0.9	2.5
874	85.8	4	1.5	0	2.5	2.8	4.3
1019	64.5	13	11.5	4.8	2	2	3.5
1020	75.8	7.5	1.5	4.3	8.8	0	2.3
1086	50.8	2.3	0.5	36	4.5	0.8	2.3
1087	66.3	8.3	4.5	15.8	2.5	0.25	0.5
1127	65.5	10.3	9.3	10.5	3.3	0.3	0.5
1128	70.8	3.3	0.8	18	2.8	0.3	4

Bone marrow nucleated cell differential counts (%) of control, leukemic PML-RARα, and leukemic FLT3^W51/PML-RARα mice are shown as mean values along with data from seven individual FLT3^W51/PML-RARα mice. Erythrocytes: nucleated erythroid cells. Other: includes monocytes, macrophages, plasma cells, mast cells. Control n = 7, PML-RARα leukemias n = 6, FLT3^W51/PML-RARα leukemias n = 7. Compared with control, FLT3^W51/PML-RARα leukemias show a statistically significant difference for all cell types. The bone marrows of PML-RARα leukemias have significantly more immature forms/blasts than the bone marrows of FLT3^W51/PML-RARα leukemias (P = .03). Some of the control and PML-RARα leukemia data have been previously reported.28 46

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