Table 1. Results in all 22 untreated... | American Society of Hematology

Table 1.

Results in all 22 untreated patients with cobalamin deficiency (pernicious anemia)

	Cobalamin-deficient patients, n = 22	Control subjects, n = 17
Total homocysteine level, μM	98.1 ± 54.4^*	11.1 ± 2.0
S-adenosylmethionine level, nM	97.9 ± 31.9	87.6 ± 37.3
Methionine level, μM	22.3 ± 10.0	17.9 ± 10.8
Cysteine level, μM	390 ± 106^*	242 ± 49
Cysteinylglycine level, μM	69.1 ± 24.4	59.0 ± 15.9
Glutathione level, μM	2.1 ± 1.3^†	4.9 ± 2.8
Cobalamin level, pM	33 ± 34^*	291 ± 115
Folate level, nM	21.5 ± 11.8	32.0 ± 17.6

	Cobalamin-deficient patients, n = 22	Control subjects, n = 17
Total homocysteine level, μM	98.1 ± 54.4^*	11.1 ± 2.0
S-adenosylmethionine level, nM	97.9 ± 31.9	87.6 ± 37.3
Methionine level, μM	22.3 ± 10.0	17.9 ± 10.8
Cysteine level, μM	390 ± 106^*	242 ± 49
Cysteinylglycine level, μM	69.1 ± 24.4	59.0 ± 15.9
Glutathione level, μM	2.1 ± 1.3^†	4.9 ± 2.8
Cobalamin level, pM	33 ± 34^*	291 ± 115
Folate level, nM	21.5 ± 11.8	32.0 ± 17.6

Significantly different from control values (P< .0001).

Significantly different from control values (P = .01).