Summary of cytogenetic and SKY findings in 16 primary and 11 relapsed MYC-induced hematopoietic tumors
| Tumor . | Phenotype . | 2n (range) . | Structural aberrations . | Chromosome losses . | Chromosome gains . |
|---|---|---|---|---|---|
| 820 | Primary | 42 (40-45) | — | 14, 17, X | 3, 7, 15, Y |
| 6021 | Primary | 41 | iso(15) | — | 15 |
| 7525 | Primary | 42 (41-43) | t(3;2), 3hsr | — | 11p+, 15 |
| 1137 | Primary | 40 (32-65) | 3, 15hsr | — | — |
| 1979 | Primary | 41 (41-42) | — | — | 17 |
| 2263 | Primary | 42 (39-43) | t(3;17), 3, 15hsr, del(4) | — | 3q+, 11p+, 15 |
| 5719 | Primary | 41 (39-43) | 3, 15hsr | — | 1, 4 |
| 5720 | Primary | 41 (40-41) | t(Y;15), 3, 15, Yhsr | X | 5, Y |
| 1936 | Primary | 40 (40-45) | — | — | — |
| 1936 R1 | Relapsed | 41 (40-42) | — | — | 15 |
| 1937 | Primary | 40 (37-41) | — | — | — |
| 1937 R1 | Relapsed | 41 (37-41) | iso(15), 3, 15hsr | — | 15 |
| 6780 | Primary | 40 (36-44) | — | 16, Y | 4, 5, 11 |
| 6780 R1 | Relapsed | 42 (41-65) | t(3;17), 3hsr | — | 3, 15, Y |
| 1232 | Primary | 41 (41-45) | iso(4), 3, 15hsr | — | 4, 16 |
| 1232 R2 | Relapsed | 41 (38-51) | t(1; 18), 11hsr | 14 | 1q+, 13, 14, 15 |
| 1232 R3 | Relapsed | 42 (41-43) | t(1;18), Rob(3;10), 11hsr | 2 | 1q+, 3, 4, 11p+, 15 |
| 966 | Primary | 41 (38-43) | — | 14, 18 | 15 |
| 966 R1 | Relapsed | 40 (38-56) | iso(4), t(13;3) | — | 2, 4, 10, 19 |
| 967 | Primary | 42 | — | — | 15, Y |
| 967 R1 | Relapsed | 39 (37-40) | 11hsr | 2, 4 | — |
| 967 R2 | Relapsed | 40 (38-41) | t(3;4), iso(4), 3, 15, Yhsr | 8, 11, X | 1, 3, 4, Y |
| 6814 | Primary | 40 (38-43) | t(3;4), t(3;15), 1, 3hsr | 7 | 15, Y |
| 6814 R1 | Relapsed | 42 (39-62) | t(3;1), 3hsr | — | 3, 5, 11p+, 15 |
| 6816 | Primary | 40 (40-41) | t(Y;15), 3, 15, Yhsr | — | — |
| 6816 R3 | Relapsed | 41 (39-43) | t(3;17), t(15;5), 3, 15hsr | 18 | 3, 5, 7, 11p+, 15 |
| 2453 R | Relapsed | 42 (40-44) | t(3;4), t(3;7), t(3;15), 3hsr | 11 | 15, Y |
| Tumor . | Phenotype . | 2n (range) . | Structural aberrations . | Chromosome losses . | Chromosome gains . |
|---|---|---|---|---|---|
| 820 | Primary | 42 (40-45) | — | 14, 17, X | 3, 7, 15, Y |
| 6021 | Primary | 41 | iso(15) | — | 15 |
| 7525 | Primary | 42 (41-43) | t(3;2), 3hsr | — | 11p+, 15 |
| 1137 | Primary | 40 (32-65) | 3, 15hsr | — | — |
| 1979 | Primary | 41 (41-42) | — | — | 17 |
| 2263 | Primary | 42 (39-43) | t(3;17), 3, 15hsr, del(4) | — | 3q+, 11p+, 15 |
| 5719 | Primary | 41 (39-43) | 3, 15hsr | — | 1, 4 |
| 5720 | Primary | 41 (40-41) | t(Y;15), 3, 15, Yhsr | X | 5, Y |
| 1936 | Primary | 40 (40-45) | — | — | — |
| 1936 R1 | Relapsed | 41 (40-42) | — | — | 15 |
| 1937 | Primary | 40 (37-41) | — | — | — |
| 1937 R1 | Relapsed | 41 (37-41) | iso(15), 3, 15hsr | — | 15 |
| 6780 | Primary | 40 (36-44) | — | 16, Y | 4, 5, 11 |
| 6780 R1 | Relapsed | 42 (41-65) | t(3;17), 3hsr | — | 3, 15, Y |
| 1232 | Primary | 41 (41-45) | iso(4), 3, 15hsr | — | 4, 16 |
| 1232 R2 | Relapsed | 41 (38-51) | t(1; 18), 11hsr | 14 | 1q+, 13, 14, 15 |
| 1232 R3 | Relapsed | 42 (41-43) | t(1;18), Rob(3;10), 11hsr | 2 | 1q+, 3, 4, 11p+, 15 |
| 966 | Primary | 41 (38-43) | — | 14, 18 | 15 |
| 966 R1 | Relapsed | 40 (38-56) | iso(4), t(13;3) | — | 2, 4, 10, 19 |
| 967 | Primary | 42 | — | — | 15, Y |
| 967 R1 | Relapsed | 39 (37-40) | 11hsr | 2, 4 | — |
| 967 R2 | Relapsed | 40 (38-41) | t(3;4), iso(4), 3, 15, Yhsr | 8, 11, X | 1, 3, 4, Y |
| 6814 | Primary | 40 (38-43) | t(3;4), t(3;15), 1, 3hsr | 7 | 15, Y |
| 6814 R1 | Relapsed | 42 (39-62) | t(3;1), 3hsr | — | 3, 5, 11p+, 15 |
| 6816 | Primary | 40 (40-41) | t(Y;15), 3, 15, Yhsr | — | — |
| 6816 R3 | Relapsed | 41 (39-43) | t(3;17), t(15;5), 3, 15hsr | 18 | 3, 5, 7, 11p+, 15 |
| 2453 R | Relapsed | 42 (40-44) | t(3;4), t(3;7), t(3;15), 3hsr | 11 | 15, Y |
— indicates none detected.