Bone marrow analysis of transgenic mice
| . | Wild type . | 730 truncation . | 717 truncation . | |||
|---|---|---|---|---|---|---|
| . | Tg, n = 3 . | Control, n = 3 . | Tg, n = 3 . | Control, n = 3 . | Tg, n = 3 . | Control, n = 3 . |
| NCC, 104/femur | 2867 ± 144 | 2654 ± 264 | 2579 ± 844 | 2433 ± 814 | 2840 ± 616 | 2815 ± 1113 |
| M/E ratio | 1.27 ± 0.09 | 1.50 ± 0.38 | 1.17 ± 0.21 | 1.40 ± 0.11 | 1.40 ± 0.75 | 1.51 ± 0.20 |
| Early myeloid, % | 15.3 ± 2.43 | 17.43 ± 8.41 | 32.33 ± 3.16 | 19.2 ± 1.22 | 31.43 ± 1.26 | 19.87 ± 9.05 |
| Late myeloid, % | 33.57 ± 8.29 | 37.23 ± 1.66 | 14.87 ± 2.98 | 35.47 ± 2.0 | 10.77 ± 1.66 | 37.9 ± 8.5 |
| Early/late ratio | 0.49 ± 0.22 | 0.47 ± 0.24 | 2.21 ± 0.33 | 0.54 ± 0.02 | 2.98 ± 0.59 | 0.57 ± 0.35 |
| . | Wild type . | 730 truncation . | 717 truncation . | |||
|---|---|---|---|---|---|---|
| . | Tg, n = 3 . | Control, n = 3 . | Tg, n = 3 . | Control, n = 3 . | Tg, n = 3 . | Control, n = 3 . |
| NCC, 104/femur | 2867 ± 144 | 2654 ± 264 | 2579 ± 844 | 2433 ± 814 | 2840 ± 616 | 2815 ± 1113 |
| M/E ratio | 1.27 ± 0.09 | 1.50 ± 0.38 | 1.17 ± 0.21 | 1.40 ± 0.11 | 1.40 ± 0.75 | 1.51 ± 0.20 |
| Early myeloid, % | 15.3 ± 2.43 | 17.43 ± 8.41 | 32.33 ± 3.16 | 19.2 ± 1.22 | 31.43 ± 1.26 | 19.87 ± 9.05 |
| Late myeloid, % | 33.57 ± 8.29 | 37.23 ± 1.66 | 14.87 ± 2.98 | 35.47 ± 2.0 | 10.77 ± 1.66 | 37.9 ± 8.5 |
| Early/late ratio | 0.49 ± 0.22 | 0.47 ± 0.24 | 2.21 ± 0.33 | 0.54 ± 0.02 | 2.98 ± 0.59 | 0.57 ± 0.35 |
Values indicate means ± SD; Early myeloid, immature myeloid cells at the myeloblast to metamyelocyte stage; Late myeloid, mature neutrophils with stab or segmented nucleus; NCC, nucleated cell count; M/E ratio, myeloid cells/erythroid cells ratio; and Early/late ratio, ratio of early myeloid cells to late myeloid cells.