Table 2. Genetic linkage analysis:... | American Society of Hematology

Table 2.

Genetic linkage analysis: chromosomes 1 and 6

Marker	cM	Affected mice, AML			DOC		^2-bχ²	P
Marker	cM	Het/Hom	^2-aχ²	P	Het/Hom	^2-aχ²	^2-bχ²	P
D1Mit231	12	32/35	0.14	—	177/160	0.86	0.5	—
D1Mit527	19.5	29/37	0.96	—	176/153	1.6	1.99	—
D1Mit123	21	29/37	0.96	—	73/69	0.11	0.99	—
D1Mit21	32.8	28/37	1.2	—	164/173	0.24	0.68	—
D1Mit303	34.8	29/38	1.2	—	60/81	3.13	0.01	—
D1Mit435	36.9	28/39	1.8	—	60/82	3.41	0.01	—
D1Mit181	42	29/37	0.96	—	67/82	1.51	0.02	—
D1Mit136	59.6	32/35	0.13	—	ND		—	—
D1Mit187	62	29/38	1.2	—	158/176	0.97	0.68	—
D1Mit194	71.5	25/41	3.89	.048	151/175	1.77	1.6	—
D1Mit425	81.6	23/42	5.59	.018	152/176	1.75	2.66	—
D1Mit15	87.9	22/45	8.00	.0047	183/186	0.02	6.48	.011
D1Mit111	92.3	20/46	10.45	.0012	162/172	0.3	7.52	.0061
D1Mit150	100	20/47	11.11	.00086	173/184	0.34	8.06	.0045
D1Mit116	100.5	25/42	4.33	.038	161/168	0.15	3.03	.082
D1Mit223	106.3	29/38	1.2	—	166/174	0.19	0.69	—
D6Mit1	2.8	35/32	0.13	—	154/169	0.7	0.46	—
D6Mit268	15.6	42/45	4.33	.038	154/168	0.61	4.9	.027
D6Mit74	20.5	46/21	9.49	.002	160/175	0.67	9.9	.0017
D6Mit93	26.3	46/21	9.49	.002	158/176	0.97	10.33	.0013
D6Mit384	27.5	47/20	11.11	.00086	153/179	2.09	13.13	.0003
D6Mit17	30.3	46/21	9.49	.002	146/186	4.82	13.72	.0002
D6Mit188	32.5	46/21	9.49	.002	150/180	2.73	12.13	.0005
D6Mit102	38.5	46/21	9.49	.002	144/185	5.11	13.93	.00019
D6Mit55	49.7	42/25	4.33	.038	153/181	2.35	6.36	.012
D6Mit198	67	32/35	0.13	—	151/177	2.06	0.85	—
D6Mit201	74.1	32/35	0.13	—	ND		—	—

Marker	cM	Affected mice, AML			DOC		^2-bχ²	P
Marker	cM	Het/Hom	^2-aχ²	P	Het/Hom	^2-aχ²	^2-bχ²	P
D1Mit231	12	32/35	0.14	—	177/160	0.86	0.5	—
D1Mit527	19.5	29/37	0.96	—	176/153	1.6	1.99	—
D1Mit123	21	29/37	0.96	—	73/69	0.11	0.99	—
D1Mit21	32.8	28/37	1.2	—	164/173	0.24	0.68	—
D1Mit303	34.8	29/38	1.2	—	60/81	3.13	0.01	—
D1Mit435	36.9	28/39	1.8	—	60/82	3.41	0.01	—
D1Mit181	42	29/37	0.96	—	67/82	1.51	0.02	—
D1Mit136	59.6	32/35	0.13	—	ND		—	—
D1Mit187	62	29/38	1.2	—	158/176	0.97	0.68	—
D1Mit194	71.5	25/41	3.89	.048	151/175	1.77	1.6	—
D1Mit425	81.6	23/42	5.59	.018	152/176	1.75	2.66	—
D1Mit15	87.9	22/45	8.00	.0047	183/186	0.02	6.48	.011
D1Mit111	92.3	20/46	10.45	.0012	162/172	0.3	7.52	.0061
D1Mit150	100	20/47	11.11	.00086	173/184	0.34	8.06	.0045
D1Mit116	100.5	25/42	4.33	.038	161/168	0.15	3.03	.082
D1Mit223	106.3	29/38	1.2	—	166/174	0.19	0.69	—
D6Mit1	2.8	35/32	0.13	—	154/169	0.7	0.46	—
D6Mit268	15.6	42/45	4.33	.038	154/168	0.61	4.9	.027
D6Mit74	20.5	46/21	9.49	.002	160/175	0.67	9.9	.0017
D6Mit93	26.3	46/21	9.49	.002	158/176	0.97	10.33	.0013
D6Mit384	27.5	47/20	11.11	.00086	153/179	2.09	13.13	.0003
D6Mit17	30.3	46/21	9.49	.002	146/186	4.82	13.72	.0002
D6Mit188	32.5	46/21	9.49	.002	150/180	2.73	12.13	.0005
D6Mit102	38.5	46/21	9.49	.002	144/185	5.11	13.93	.00019
D6Mit55	49.7	42/25	4.33	.038	153/181	2.35	6.36	.012
D6Mit198	67	32/35	0.13	—	151/177	2.06	0.85	—
D6Mit201	74.1	32/35	0.13	—	ND		—	—

Het/Hom indicates the heterozygous-homozygous ratio;

χ², χ² test of homogeneity;

χ², χ² test of independence for affected vs unaffected mice; and ND, not determined. Only values for P < .05 are shown; otherwise — appears.