Total duration of platelet support, duration within each period of platelet support, and transfusion interval in cycle 1
| . | Treatment group . | . | |
|---|---|---|---|
| Test (n = 52) . | Reference (n = 51) . | P . | |
| Total duration of platelet support, mean ± SD, d | 15.2 ± 11.2 | 12.7 ± 12.4 | .29 |
| Duration of platelet support by period within cycle 1, mean ± SD, d | |||
| Period 1 (no. of patients) | 11.7 ± 9.5 (52) | 10.1 ± 11.7 (51) | ≥.45 |
| Period 2 (no. of patients) | 7.5 ± 7.2 (22) | 8.0 ± 7.9 (14) | |
| Period 3 (no. of patients) | 15.0 (1) | 5.0 ± 6.9 (3) | |
| Time between transfusions during first period of platelet support, mean ± SD, d | 3.0 ± 1.23 | 3.4 ± 1.21 | .13 |
| . | Treatment group . | . | |
|---|---|---|---|
| Test (n = 52) . | Reference (n = 51) . | P . | |
| Total duration of platelet support, mean ± SD, d | 15.2 ± 11.2 | 12.7 ± 12.4 | .29 |
| Duration of platelet support by period within cycle 1, mean ± SD, d | |||
| Period 1 (no. of patients) | 11.7 ± 9.5 (52) | 10.1 ± 11.7 (51) | ≥.45 |
| Period 2 (no. of patients) | 7.5 ± 7.2 (22) | 8.0 ± 7.9 (14) | |
| Period 3 (no. of patients) | 15.0 (1) | 5.0 ± 6.9 (3) | |
| Time between transfusions during first period of platelet support, mean ± SD, d | 3.0 ± 1.23 | 3.4 ± 1.21 | .13 |
All transfusions for the ITT population were recorded during the 56-day transfusion period. The period of platelet support was defined as the number of days from the first study transfusion to the last platelet transfusion. If an interval of 7 or more days without platelet transfusions occurred, the last platelet transfusion before the interval with no platelet transfusion was treated as the last platelet transfusion for that period of support. If platelet transfusions were resumed, the length of subsequent periods of platelet support was added to the first period of platelet support to determine the total period of platelet support during the 56-day transfusion cycle. Thus, patients could have multiple periods of platelet transfusion during a 56-day cycle.