Time-varying risk factors for death after day 95: lymphocytopenia
| Covariate . | Univariate, RR . | 95% CI . | Multivariable, RR . | 95% CI . |
|---|---|---|---|---|
| CMV disease, time dependent | 3.1 | 1.7, 5.67-150 | 2.37-151 | 1.2, 4.27-150 |
| Lymphocytopenia, time dependent | ||||
| Fewer than 100 lymphocytes/mm3 | 7.1 | 2.5, 19.97-150 | — | — |
| Fewer than 300 lymphocytes/mm3 | 5.9 | 3.3, 10.57-150 | 3.67-151 | 1.9, 6.77-150 |
| Covariate . | Univariate, RR . | 95% CI . | Multivariable, RR . | 95% CI . |
|---|---|---|---|---|
| CMV disease, time dependent | 3.1 | 1.7, 5.67-150 | 2.37-151 | 1.2, 4.27-150 |
| Lymphocytopenia, time dependent | ||||
| Fewer than 100 lymphocytes/mm3 | 7.1 | 2.5, 19.97-150 | — | — |
| Fewer than 300 lymphocytes/mm3 | 5.9 | 3.3, 10.57-150 | 3.67-151 | 1.9, 6.77-150 |
— indicates results not significant
P ≤ .01.
Candidates for the final multivariable model included CMV disease (viral monitoring parameters not included), aspergillosis, chronic clinical-extensive GVHD, CMV-specific T-cell negativity, CD4 cells, age, donor CMV serostatus, underlying disease, donor type, and lymphopenia.