Number of gold particles per platelet section after labeling with the anti-TPα receptor
| Platelets . | Gold particles per platelet section, no.* . | Mean surface area per platelet section, μm2 . | ||
|---|---|---|---|---|
| Surface . | Internal membranes . | Total . | ||
| Controls | ||||
| Unstimulated | 16.60 ± 7.94 | 51.71 ± 18.67 | 68.32 ± 22.92 | 2.36 ± 0.92 |
| I-BOP stimulated | 32.84 ± 16.90 | 85.69 ± 49.93 | 118.53 ± 61.36 | 3.19 ± 1.27 |
| Desensitized | 15.89 ± 6.16 | 59.17 ± 22.71 | 75.06 ± 23.54 | 2.52 ± 1.12 |
| Patient ML | ||||
| Unstimulated | 18.53 ± 11.16 | 51.85 ± 29.78 | 70.38 ± 37.84 | 2.58 ± 0.93 |
| I-BOP stimulated | 32.67 ± 11.18 | 103.92 ± 50.46 | 136.59 ± 58.68 | 2.8 ± 1.12 |
| Platelets . | Gold particles per platelet section, no.* . | Mean surface area per platelet section, μm2 . | ||
|---|---|---|---|---|
| Surface . | Internal membranes . | Total . | ||
| Controls | ||||
| Unstimulated | 16.60 ± 7.94 | 51.71 ± 18.67 | 68.32 ± 22.92 | 2.36 ± 0.92 |
| I-BOP stimulated | 32.84 ± 16.90 | 85.69 ± 49.93 | 118.53 ± 61.36 | 3.19 ± 1.27 |
| Desensitized | 15.89 ± 6.16 | 59.17 ± 22.71 | 75.06 ± 23.54 | 2.52 ± 1.12 |
| Patient ML | ||||
| Unstimulated | 18.53 ± 11.16 | 51.85 ± 29.78 | 70.38 ± 37.84 | 2.58 ± 0.93 |
| I-BOP stimulated | 32.67 ± 11.18 | 103.92 ± 50.46 | 136.59 ± 58.68 | 2.8 ± 1.12 |
Experimental procedures were as for Table I. Results are ± SD. For controls done with an irrelevant rabbit antibody, the number of gold particles evaluated for 100-platelet sections constituted, respectively. 0.74% (unstimulated) and 0.48% (stimulated) of the total number of gold particles seen with the anti-TPα antibody.