Surface expression of homing receptors by human LV'VFas+ T cells stimulated with anti-CD3 and anti-CD28 or with anti-CD3 alone
| T-cell subset . | PBLs, % mean (range) . | Stimulated T cells, % mean (range) . | |||
|---|---|---|---|---|---|
| Anti-CD3 and anti-CD28 . | Anti-CD3 . | ||||
| Untransduced . | LV'VFas+unselected . | LV'VFas+ enriched . | LV'VFas+enriched . | ||
| CD62L+ | 50.5 (21.6-66.7) | 50.9 (29.3-79.5) | 53.9 (31.5-81.0) | 51.0 (30.9-83.0) | 7.4 (6.2-8.7) |
| CCR7+ | 51.8 (30.7-74.8) | 34.5 (18.8-52.6) | 31.5 (17.9-48.8) | 31.0 (18.4-51.0) | 3.8 (2.8-4.5) |
| CD49d+ | 94.3 (83.4-99.5) | 99.2 (98.9-99.5) | 99.3 (98.9-99.8) | 99.5 (99.1-99.9) | 99.4 (99.0-99.8) |
| T-cell subset . | PBLs, % mean (range) . | Stimulated T cells, % mean (range) . | |||
|---|---|---|---|---|---|
| Anti-CD3 and anti-CD28 . | Anti-CD3 . | ||||
| Untransduced . | LV'VFas+unselected . | LV'VFas+ enriched . | LV'VFas+enriched . | ||
| CD62L+ | 50.5 (21.6-66.7) | 50.9 (29.3-79.5) | 53.9 (31.5-81.0) | 51.0 (30.9-83.0) | 7.4 (6.2-8.7) |
| CCR7+ | 51.8 (30.7-74.8) | 34.5 (18.8-52.6) | 31.5 (17.9-48.8) | 31.0 (18.4-51.0) | 3.8 (2.8-4.5) |
| CD49d+ | 94.3 (83.4-99.5) | 99.2 (98.9-99.5) | 99.3 (98.9-99.8) | 99.5 (99.1-99.9) | 99.4 (99.0-99.8) |
Data are representative of independent experiments from 9 different donors. In 3 experiments, PBLs were stimulated with anti-CD3 alone for comparison.