Adverse events related to treatment with R115777
| . | No. (%) of patients affected . | |
|---|---|---|
| Any grade . | Grade 3 or 4 . | |
| Nausea/vomiting | 22 (55) | 0 |
| Fatigue | 19 (48) | 1 (3) |
| Skin rash | 13 (33) | 4 (10) |
| Diarrhea | 13 (33) | 0 |
| Pain | 10 (25) | 0 |
| Elevated transaminase/bilirubin levels | 9 (23) | 2 (5) |
| Elevated creatinine levels | 9 (23) | 0 |
| Peripheral neuropathy | 7 (18) | 3 (8) |
| . | No. (%) of patients affected . | |
|---|---|---|
| Any grade . | Grade 3 or 4 . | |
| Nausea/vomiting | 22 (55) | 0 |
| Fatigue | 19 (48) | 1 (3) |
| Skin rash | 13 (33) | 4 (10) |
| Diarrhea | 13 (33) | 0 |
| Pain | 10 (25) | 0 |
| Elevated transaminase/bilirubin levels | 9 (23) | 2 (5) |
| Elevated creatinine levels | 9 (23) | 0 |
| Peripheral neuropathy | 7 (18) | 3 (8) |