Univariate and multivariable analysis of factors associated with TT-CMV infection during period 2
Covariate . | Univariate model . | Multivariate model . | ||
---|---|---|---|---|
Odds ratio (95% CI) . | P . | Odds ratio (95% CI) . | P . | |
Blood product support5-150 | ||||
CMV-seronegative products | 1.01 (1.00-1.02) | .05 | 1.01 (0.99-1.03) | .13 |
Filtered RBC from CMV+donor | 1.14 (0.99-1.31) | .06 | 1.32 (1.08-1.61) | .006 |
Filtered PLT from CMV+donor | 0.55 (0.15-1.95) | .35 | 0.48 (0.17-1.32) | .15 |
LR apheresis PLT from CMV+donor | 1.03 (1.00-1.06) | .05 | 1.02 (0.97-1.08) | .42 |
Other factors | ||||
Transplant type | ||||
Autologous | 1.0 (referent) | .39 | NE | |
Matched allogeneic | 1.82 (0.54-6.21) | .34 | NE | |
Mismatched/unrelated donor allogeneic | 0.89 (0.25-3.23) | .87 | NE |
Covariate . | Univariate model . | Multivariate model . | ||
---|---|---|---|---|
Odds ratio (95% CI) . | P . | Odds ratio (95% CI) . | P . | |
Blood product support5-150 | ||||
CMV-seronegative products | 1.01 (1.00-1.02) | .05 | 1.01 (0.99-1.03) | .13 |
Filtered RBC from CMV+donor | 1.14 (0.99-1.31) | .06 | 1.32 (1.08-1.61) | .006 |
Filtered PLT from CMV+donor | 0.55 (0.15-1.95) | .35 | 0.48 (0.17-1.32) | .15 |
LR apheresis PLT from CMV+donor | 1.03 (1.00-1.06) | .05 | 1.02 (0.97-1.08) | .42 |
Other factors | ||||
Transplant type | ||||
Autologous | 1.0 (referent) | .39 | NE | |
Matched allogeneic | 1.82 (0.54-6.21) | .34 | NE | |
Mismatched/unrelated donor allogeneic | 0.89 (0.25-3.23) | .87 | NE |
CMV indicates cytomegalovirus; CI, confidence interval; RBC, red blood cell product; PLT, platelet product; LR, leukoreduced; and NE, not evaluated.
Blood product support covariates expressed as odds for TT-CMV for each additional blood product per 100 days of follow-up.