Patient characteristics: bax/bcl-2 ratio
Total no. | 255 |
Male | 140 |
Female | 115 |
No. of patients | |
Younger than 60 y | 116 |
Older than 60 y | 139 |
WBC, × 109/L | |
Less than 50 | 161 |
50-100 | 58 |
More than 100 | 36 |
Positive cases (bax/bcl-2 less than 0.3) | 130/255 (51%) |
CR rate, all patients | 60.2% |
bax/bcl-2 less than 0.3 | 45% |
bax/bcl-2 greater than 0.3 | 79% (P = .000 01) |
Median duration of survival, all patients* | 39 |
bax/bcl-2 less than 0.3 | 27 (P = .000 01) |
bax/bcl-2 greater than 0.3 | 53 |
Median disease free survival, all patients* | 38 |
bax/bcl-2 less than 0.3 | 24 (P = .019) |
bax/bcl-2 greater than 0.3 | 48 |
Total no. | 255 |
Male | 140 |
Female | 115 |
No. of patients | |
Younger than 60 y | 116 |
Older than 60 y | 139 |
WBC, × 109/L | |
Less than 50 | 161 |
50-100 | 58 |
More than 100 | 36 |
Positive cases (bax/bcl-2 less than 0.3) | 130/255 (51%) |
CR rate, all patients | 60.2% |
bax/bcl-2 less than 0.3 | 45% |
bax/bcl-2 greater than 0.3 | 79% (P = .000 01) |
Median duration of survival, all patients* | 39 |
bax/bcl-2 less than 0.3 | 27 (P = .000 01) |
bax/bcl-2 greater than 0.3 | 53 |
Median disease free survival, all patients* | 38 |
bax/bcl-2 less than 0.3 | 24 (P = .019) |
bax/bcl-2 greater than 0.3 | 48 |
Survival parameters are expressed in weeks.