Table 1.

Summary of diagnoses and International Prognostic Scoring System (IPSS) risk groups, reduced-intensity and standard conditioning

Median age, y (range)Reduced-intensity (n = 60)Standard conditioning (n = 61)
Sibling
51 (27-70)
VUD
49 (21-58)
Total
50 (21-70)
Sibling
37 (17-59)
VUD
28 (18-43)
Total
33 (17-59)
Myelodysplastic syndrome 17 31 48 22 14 36 
 RA/RC 11 14 10 18 
 RAEB-I 10 
 RAEB-II 
 RAEB-t/TLD-AML 12 10 
 CMML 1  
De novo acute myeloid leukemia 12 17 25  
IPSS risk groups       
 High* 16 18 34 26 12 38 
 Intermediate-2 10 14 
 Intermediate-1 12 12 
 Low 
Median age, y (range)Reduced-intensity (n = 60)Standard conditioning (n = 61)
Sibling
51 (27-70)
VUD
49 (21-58)
Total
50 (21-70)
Sibling
37 (17-59)
VUD
28 (18-43)
Total
33 (17-59)
Myelodysplastic syndrome 17 31 48 22 14 36 
 RA/RC 11 14 10 18 
 RAEB-I 10 
 RAEB-II 
 RAEB-t/TLD-AML 12 10 
 CMML 1  
De novo acute myeloid leukemia 12 17 25  
IPSS risk groups       
 High* 16 18 34 26 12 38 
 Intermediate-2 10 14 
 Intermediate-1 12 12 
 Low 

RA indicates refractory anemia; RC, refractory cytopenias; RAEB, refractory anemia with excess blasts; TLD-AML, tri-lineage dysplasia acute myeloid leukemia; and CMML, chronic myelomonocytic leukemia.

*

Although the IPSS is not used in AML, for the purpose of this analysis, all AMLs have been classified as “high” risk.