Table 1.

VWF parameters in type 2A and 2B VWD patients

PatientVWF:antigen, %R:cof,*%Gene analysis
2A-1 86 9.6 ND 
 -2 42 4.8 ND  
 -3 35 < 4.8 ND 
2B-1 42 4.8 Arg545Cys  
 -2* 34 4.8 Arg545Cys 
 -3 36 12 Val553Met 
 -4 42 12 Val553Met 
PatientVWF:antigen, %R:cof,*%Gene analysis
2A-1 86 9.6 ND 
 -2 42 4.8 ND  
 -3 35 < 4.8 ND 
2B-1 42 4.8 Arg545Cys  
 -2* 34 4.8 Arg545Cys 
 -3 36 12 Val553Met 
 -4 42 12 Val553Met 

R:cof indicates ristocetin cofactor activity of VWF; ND, not determined.

*

Patient 2B-2 is the son of 2B-1.

Patients 2B-3 and 2B-4 are brothers.

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