Table 2.

Engraftment of hCD45+ cells in bone marrow and peripheral blood in NOD/SCID mice

Mice with reconstituted
cells/transplant
recipients, no.
CD45+ cells
in BM of
recipients, %
CD45+ cells
in PB of
recipients, %
Accessory cells 0/3 ND ND 
Precoculture 4/5 1.67 ± 2.06 ND  
Stroma free, 2 wk 0/3 ND ND  
Primary, 2 wk 3/5 0.79 ± 1.00 ND  
hTERT, 2 wk 5/5 1.65 ± 1.33 ND  
Primary, 4 wk 5/5 5.88 ± 4.86 0.15 ± 0.09  
hTERT, 4 wk 5/5 9.67 ± 5.57* 0.27 ± 0.23 
Mice with reconstituted
cells/transplant
recipients, no.
CD45+ cells
in BM of
recipients, %
CD45+ cells
in PB of
recipients, %
Accessory cells 0/3 ND ND 
Precoculture 4/5 1.67 ± 2.06 ND  
Stroma free, 2 wk 0/3 ND ND  
Primary, 2 wk 3/5 0.79 ± 1.00 ND  
hTERT, 2 wk 5/5 1.65 ± 1.33 ND  
Primary, 4 wk 5/5 5.88 ± 4.86 0.15 ± 0.09  
hTERT, 4 wk 5/5 9.67 ± 5.57* 0.27 ± 0.23 

ND indicates hCD45% values below the cutoff level (0.1%) ± standard deviation.

*

P < .05, compared with precoculture group (Mann-Whitney U test).

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