CD437-mediated increase in annexin V staining, fold-increase in annexin-positive cells compared with control
| Cell line . | Annexin V+ cells, %, on exposure to CD437 . | |||
|---|---|---|---|---|
| 100 nM . | 250 nM . | 500 nM . | 1000 nM . | |
| WSU-CLL | 1.0 | 1.0 | 2.4 | 3.2 |
| ALL-REH | 1.0 | 1.0 | 1.7 | 2.0 |
| Cell line . | Annexin V+ cells, %, on exposure to CD437 . | |||
|---|---|---|---|---|
| 100 nM . | 250 nM . | 500 nM . | 1000 nM . | |
| WSU-CLL | 1.0 | 1.0 | 2.4 | 3.2 |
| ALL-REH | 1.0 | 1.0 | 1.7 | 2.0 |
Cells were exposed to various concentrations of CD437 (indicated by the column headings) or to vehicle alone for 12 hours, and the percentages of annexin-positive and propidium iodide–negative staining cells were determined as described in “Materials and methods.” The results shown are a representative of two independent experiments.