T-cell restoration in transgenic mice
Mouse . | Thymus . | Spleen . | ||
---|---|---|---|---|
CD4 . | CD8 . | CD4 . | CD8 . | |
Knockout | 0.19 ± 0.06 × 106 | 0.10 ± 0.02 × 106 | 2.3 ± 1.8 × 106 | 1.2 ± 0.8 × 106 |
C57BL/6 | 5.1 ± 2.0 × 106 | 2.9 ± 1.5 × 106 | 18 ± 5 × 106 | 8.9 ± 2.7 × 106 |
Transgenic F | 4.0 ± 0.9 × 106 | 3.3 ± 1.0 × 106 | 16 ± 5 × 106 | 7.7 ± 1.9 × 106 |
Mouse . | Thymus . | Spleen . | ||
---|---|---|---|---|
CD4 . | CD8 . | CD4 . | CD8 . | |
Knockout | 0.19 ± 0.06 × 106 | 0.10 ± 0.02 × 106 | 2.3 ± 1.8 × 106 | 1.2 ± 0.8 × 106 |
C57BL/6 | 5.1 ± 2.0 × 106 | 2.9 ± 1.5 × 106 | 18 ± 5 × 106 | 8.9 ± 2.7 × 106 |
Transgenic F | 4.0 ± 0.9 × 106 | 3.3 ± 1.0 × 106 | 16 ± 5 × 106 | 7.7 ± 1.9 × 106 |
The values are the total number of CD4 and CD8 single positive cells in the thymus and spleen of the mouse. Averages with standard deviations were derived from the separate analyses of 3 thymuses and 5 spleens.