Table 1.

T-cell restoration in transgenic mice

MouseThymusSpleen
CD4CD8CD4CD8
Knockout 0.19 ± 0.06 × 106 0.10 ± 0.02 × 106 2.3 ± 1.8 × 106 1.2 ± 0.8 × 106 
C57BL/6 5.1 ± 2.0 × 106 2.9 ± 1.5 × 106 18 ± 5 × 106 8.9 ± 2.7 × 106 
Transgenic F 4.0 ± 0.9 × 106 3.3 ± 1.0 × 106 16 ± 5 × 106 7.7 ± 1.9 × 106 
MouseThymusSpleen
CD4CD8CD4CD8
Knockout 0.19 ± 0.06 × 106 0.10 ± 0.02 × 106 2.3 ± 1.8 × 106 1.2 ± 0.8 × 106 
C57BL/6 5.1 ± 2.0 × 106 2.9 ± 1.5 × 106 18 ± 5 × 106 8.9 ± 2.7 × 106 
Transgenic F 4.0 ± 0.9 × 106 3.3 ± 1.0 × 106 16 ± 5 × 106 7.7 ± 1.9 × 106 

The values are the total number of CD4 and CD8 single positive cells in the thymus and spleen of the mouse. Averages with standard deviations were derived from the separate analyses of 3 thymuses and 5 spleens.

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