Values for 2-point LOD score
| Order . | Comp . | McM . | FcM . | Logarithm of the odds (LOD score) . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| θ = 0 . | θ = .01 . | θ = .05 . | θ = .1 . | θ = .2 . | θ = .3 . | θ = .4 . | ||||
| D16S420 | 31 130 | 51.65 | 43.44 | -infini | 1.32 | 1.75 | 1.71 | 1.31 | 0.77 | 0.25 |
| D16S3093 | 36 625 | 52.51 | 52.12 | -infini | −0.74 | −0.11 | 0.09 | 0.18 | 0.13 | 0.04 |
| D16S3131 | 37 256 | 52.61 | 53.17 | -infini | −0.15 | 0.40 | 0.52 | 0.45 | 0.26 | 0.08 |
| D16S261 | 40 460 | 53.69 | 64.17 | 3.39* | 3.32* | 3.03* | 2.67 | 1.91 | 1.13 | 0.38 |
| D16S690 | 52 906 | 53.69 | 65.97 | 3.39* | 3.32* | 3.03* | 2.67 | 1.91 | 1.13 | 0.38 |
| D16S3080 | 55 810 | 53.69 | 66.39 | 1.88 | 1.84 | 1.68 | 1.48 | 1.05 | 0.61 | 0.20 |
| D16S409 | 62 310 | 53.69 | 67.33 | 3.08* | 3.02* | 2.77 | 2.45 | 1.78 | 1.06 | 0.36 |
| D16S419 | 63 668 | 56.83 | 78.35 | -infini | 1.32 | 1.75 | 1.71 | 1.31 | 0.77 | 0.25 |
| D16S3039 | 65 124 | 56.83 | 92.29 | -infini | 1.32 | 1.73 | 1.68 | 1.26 | 0.72 | 0.23 |
| D16S3096 | 91 611 | 69.66 | 120.05 | -infini | −1.39 | −0.17 | 0.20 | 0.34 | 0.24 | 0.08 |
| Order . | Comp . | McM . | FcM . | Logarithm of the odds (LOD score) . | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| θ = 0 . | θ = .01 . | θ = .05 . | θ = .1 . | θ = .2 . | θ = .3 . | θ = .4 . | ||||
| D16S420 | 31 130 | 51.65 | 43.44 | -infini | 1.32 | 1.75 | 1.71 | 1.31 | 0.77 | 0.25 |
| D16S3093 | 36 625 | 52.51 | 52.12 | -infini | −0.74 | −0.11 | 0.09 | 0.18 | 0.13 | 0.04 |
| D16S3131 | 37 256 | 52.61 | 53.17 | -infini | −0.15 | 0.40 | 0.52 | 0.45 | 0.26 | 0.08 |
| D16S261 | 40 460 | 53.69 | 64.17 | 3.39* | 3.32* | 3.03* | 2.67 | 1.91 | 1.13 | 0.38 |
| D16S690 | 52 906 | 53.69 | 65.97 | 3.39* | 3.32* | 3.03* | 2.67 | 1.91 | 1.13 | 0.38 |
| D16S3080 | 55 810 | 53.69 | 66.39 | 1.88 | 1.84 | 1.68 | 1.48 | 1.05 | 0.61 | 0.20 |
| D16S409 | 62 310 | 53.69 | 67.33 | 3.08* | 3.02* | 2.77 | 2.45 | 1.78 | 1.06 | 0.36 |
| D16S419 | 63 668 | 56.83 | 78.35 | -infini | 1.32 | 1.75 | 1.71 | 1.31 | 0.77 | 0.25 |
| D16S3039 | 65 124 | 56.83 | 92.29 | -infini | 1.32 | 1.73 | 1.68 | 1.26 | 0.72 | 0.23 |
| D16S3096 | 91 611 | 69.66 | 120.05 | -infini | −1.39 | −0.17 | 0.20 | 0.34 | 0.24 | 0.08 |
Values for 2-point LOD score (MLINK) for linkage between familial multiple coagulation factor deficiency (FMFD) and selected chromosome 16 markers based on the 2 families, obtained at different recombination fractions. Male and female map distances are given in centimorgans (McM and FcM, respectively). Comp refers to a composite location in megabases according to the LDB database.
Indicates LOD scores greater than 3.0, providing an odds ratio of linkage versus free recombination of greater than 1000:1.